COVID-19 extra-pulmonary features include several endocrine manifestations and these are
becoming strongly clinically relevant in patients affected influencing disease severity and …

Recent work has identified three distinct classes of viral membrane fusion proteins based on
structural criteria. In addition, there are at least four distinct mechanisms by which viral fusion …

Fusion with, and subsequent entry into, the host cell is one of the critical steps in the life
cycle of enveloped viruses. For Middle East respiratory syndrome coronavirus (MERS-CoV) …

Two mutations in the protein α-synuclein (A30P and A53T) are linked to an autosomal
dominant form of Parkinson's disease. Both mutations accelerate the formation of prefibrillar …

Calcium-permeable pores formed by small oligomers of amyloid proteins are the primary
pathologic species in Alzheimer's and Parkinson's diseases. However, the molecular …

Liposomes are being increasingly utilized to deliver drugs, enzymes, antisense
oligonucleotides, and genes to various therapeutic targets. Liposome-mediated delivery of …

▪ Abstract Significant progress has been made in elucidating the mechanisms of viral
membrane fusion proteins; both those that function at low, as well as those that function at …

Non-lamellar-forming lipids play an important role in determining the physical properties of
membranes. They affect the activity of membrane proteins and peptides. In addition …

Enormous efforts have been made to produce a protective vaccine against human
immunodeficiency virus type 1; there has been little success. However, the identification of …

While antimicrobial and cytolytic peptides exert their effects on cells largely by interacting
with the lipid bilayers of their membranes, the influence of the cell membrane lipid …