Hypocalcemia in COVID-19: Prevalence, clinical significance and therapeutic implications

L di Filippo, M Doga, S Frara, A Giustina - Reviews in Endocrine and …, 2022 - Springer
COVID-19 extra-pulmonary features include several endocrine manifestations and these are
becoming strongly clinically relevant in patients affected influencing disease severity and …

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme

JM White, SE Delos, M Brecher… - Critical reviews in …, 2008 - Taylor & Francis
Recent work has identified three distinct classes of viral membrane fusion proteins based on
structural criteria. In addition, there are at least four distinct mechanisms by which viral fusion …

Ca2+ Ions Promote Fusion of Middle East Respiratory Syndrome Coronavirus with Host Cells and Increase Infectivity

MR Straus, T Tang, AL Lai, A Flegel, M Bidon… - Journal of …, 2020 - journals.asm.org
Fusion with, and subsequent entry into, the host cell is one of the critical steps in the life
cycle of enveloped viruses. For Middle East respiratory syndrome coronavirus (MERS-CoV) …

Common molecular mechanism of amyloid pore formation by Alzheimer's β-amyloid peptide and α-synuclein

C Di Scala, N Yahi, S Boutemeur, A Flores… - Scientific reports, 2016 - nature.com
Calcium-permeable pores formed by small oligomers of amyloid proteins are the primary
pathologic species in Alzheimer's and Parkinson's diseases. However, the molecular …

Vesicle permeabilization by protofibrillar α-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism

MJ Volles, PT Lansbury - Biochemistry, 2002 - ACS Publications
Two mutations in the protein α-synuclein (A30P and A53T) are linked to an autosomal
dominant form of Parkinson's disease. Both mutations accelerate the formation of prefibrillar …

Current status of pH-sensitive liposomes in drug delivery

DC Drummond, M Zignani, JC Leroux - Progress in lipid research, 2000 - Elsevier
Liposomes are being increasingly utilized to deliver drugs, enzymes, antisense
oligonucleotides, and genes to various therapeutic targets. Liposome-mediated delivery of …

Virus-cell and cell-cell fusion

LD Hernandez, LR Hoffman… - Annual review of cell …, 1996 - annualreviews.org
▪ Abstract Significant progress has been made in elucidating the mechanisms of viral
membrane fusion proteins; both those that function at low, as well as those that function at …

Lipid polymorphism and protein–lipid interactions

RM Epand - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1998 - Elsevier
Non-lamellar-forming lipids play an important role in determining the physical properties of
membranes. They affect the activity of membrane proteins and peptides. In addition …

The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design

M Montero, NE van Houten, X Wang… - … and molecular biology …, 2008 - journals.asm.org
Enormous efforts have been made to produce a protective vaccine against human
immunodeficiency virus type 1; there has been little success. However, the identification of …

[HTML][HTML] Lipid-induced conformation and lipid-binding properties of cytolytic and antimicrobial peptides: determination and biological specificity

SE Blondelle, K Lohner, MI Aguilar - Biochimica et Biophysica Acta (BBA) …, 1999 - Elsevier
While antimicrobial and cytolytic peptides exert their effects on cells largely by interacting
with the lipid bilayers of their membranes, the influence of the cell membrane lipid …