Brain circuits for pain and its treatment

N Mercer Lindsay, C Chen, G Gilam… - Science translational …, 2021 - science.org
Pain is a multidimensional experience with sensory-discriminative, affective-motivational,
and cognitive-evaluative components. Pain aversiveness is one principal cause of suffering …

The role of calcitonin gene–related peptide in peripheral and central pain mechanisms including migraine

S Iyengar, MH Ossipov, KW Johnson - Pain, 2017 - journals.lww.com
Calcitonin gene–related peptide (CGRP) is a 37-amino acid peptide found primarily in the C
and Aδ sensory fibers arising from the dorsal root and trigeminal ganglia, as well as the …

Triple representation of language, working memory, social and emotion processing in the cerebellum: convergent evidence from task and seed-based resting-state …

X Guell, JDE Gabrieli, JD Schmahmann - Neuroimage, 2018 - Elsevier
Delineation of functional topography is critical to the evolving understanding of the
cerebellum's role in a wide range of nervous system functions. We used data from the …

Consensus paper: cerebellum and emotion

M Adamaszek, F D'Agata, R Ferrucci, C Habas… - The Cerebellum, 2017 - Springer
Over the past three decades, insights into the role of the cerebellum in emotional processing
have substantially increased. Indeed, methodological refinements in cerebellar lesion …

[HTML][HTML] The cerebellum and the Mirror Neuron System: A matter of inhibition? From neurophysiological evidence to neuromodulatory implications. A narrative review

A Antonioni, EM Raho, S Straudi, E Granieri… - Neuroscience & …, 2024 - Elsevier
Mirror neurons show activity during both the execution (AE) and observation of actions (AO).
The Mirror Neuron System (MNS) could be involved during motor imagery (MI) as well …

Consensus paper: the role of the cerebellum in perceptual processes

O Baumann, RJ Borra, JM Bower, KE Cullen, C Habas… - The Cerebellum, 2015 - Springer
Various lines of evidence accumulated over the past 30 years indicate that the cerebellum,
long recognized as essential for motor control, also has considerable influence on …

Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis

H Fujita, T Kodama, S Du Lac - Elife, 2020 - elifesciences.org
The cerebellar vermis, long associated with axial motor control, has been implicated in a
surprising range of neuropsychiatric disorders and cognitive and affective functions …

Psychological processing in chronic pain: a neural systems approach

LE Simons, I Elman, D Borsook - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Our understanding of chronic pain involves complex brain circuits that include sensory,
emotional, cognitive and interoceptive processing. The feed-forward interactions between …

Frontostriatal gating of tinnitus and chronic pain

JP Rauschecker, ES May, A Maudoux… - Trends in cognitive …, 2015 - cell.com
Tinnitus and chronic pain are sensory–perceptual disorders associated with negative affect
and high impact on well-being and behavior. It is now becoming increasingly clear that …

The medial prefrontal cortex as a central hub for mental comorbidities associated with chronic pain

KK Kummer, M Mitrić, T Kalpachidou… - International journal of …, 2020 - mdpi.com
Chronic pain patients frequently develop and suffer from mental comorbidities such as
depressive mood, impaired cognition, and other significant constraints of daily life, which …