Simple Summary The Casein Kinase 1 (CK1) family of serine-threonine specific protein
kinases regulates the activity of key regulatory proteins and signaling pathways being …

Mitogen-activated extracellular signal-regulated kinase 1 and 2 (MEK1/2) are the critical
components of the mitogen-activated protein kinase/extracellular signal-regulated kinase 1 …

Protein kinase inhibitors are currently being used as a major therapeutic option to target
cancer, diabetes and neurodegenerative diseases. In recent years, pyruvate …

Aurora kinase B (AURKB) is known to play a carcinogenic role in a variety of cancers, but its
underlying mechanism in liver cancer is unknown. This study aimed to investigate the role of …

Aurora kinase B (AURKB) is a type of functional kinase with primary functions of participating
in cell mitosis, which has been identified to be involved in the occurrence and development …

Aurora kinase B (AURKB), an essential regulator in the process of mitosis, has been
revealed through various studies to have a significant role in cancer development and …

Breast cancer stem cells (BCSCs) play a critical role in chemoresistance, metastasis, and
poor prognosis of breast cancer. BCSCs are mostly dormant, and therefore, activating them …

Aurora kinases are essential players in mammalian cell division. These kinases are involved
in the regulation of spindle dynamics, microtubule–kinetochore interactions, and …

Breast cancer is a leading cause of cancer-related deaths in females. Triple-negative breast
cancer (TNBC) subtype is the most aggressive form of breast cancer that lacks biomarkers …

Esophageal cancer (EC) is one of the most fatal malignancies worldwide, with a dramatic
increase in incidence in the western world occurring over the past few decades …