[HTML][HTML] Practical considerations for sample size calculation for cluster randomized trials

C Leyrat, S Eldridge, M Taljaard, K Hemming - Journal of Epidemiology …, 2024 - Elsevier
Cluster randomized trials are an essential design in public health and medical research,
when individual randomization is infeasible or undesirable for scientific or logistical reasons …

Sample size determination for external pilot cluster randomised trials with binary feasibility outcomes: a tutorial

K Hemming, M Taljaard, E Gkini, J Bishop - Pilot and Feasibility Studies, 2023 - Springer
Justifying sample size for a pilot trial is a reporting requirement, but few pilot trials report a
clear rationale for their chosen sample size. Unlike full-scale trials, pilot trials should not be …

Maintaining the validity of inference from linear mixed models in stepped-wedge cluster randomized trials under misspecified random-effects structures

Y Ouyang, M Taljaard, AB Forbes… - Statistical Methods in …, 2024 - journals.sagepub.com
Linear mixed<? show [AQ ID= GQ2 POS=-18pt]?><? show [AQ ID= GQ4]?><? show [AQ ID=
GQ5 POS= 12pt]?> models are commonly used in analyzing stepped-wedge cluster …

Sample size calculations for stepped wedge designs with treatment effects that may change with the duration of time under intervention

JP Hughes, WY Lee, AB Troxel, PJ Heagerty - Prevention Science, 2024 - Springer
The stepped wedge design is often used to evaluate interventions as they are rolled out
across schools, health clinics, communities, or other clusters. Most models used in the …

Estimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer's and related dementias

Y Ouyang, F Li, X Li, J Bynum, V Mor, M Taljaard - Trials, 2024 - Springer
Abstract Background Cluster randomized trials (CRTs) are increasingly important for
evaluating interventions embedded in health care systems. An essential parameter in …

Sample size requirements for testing treatment effect heterogeneity in cluster randomized trials with binary outcomes

L Maleyeff, R Wang, S Haneuse, F Li - Statistics in Medicine, 2023 - Wiley Online Library
Cluster randomized trials (CRTs) refer to a popular class of experiments in which
randomization is carried out at the group level. While methods have been developed for …

Sample size and power calculation for testing treatment effect heterogeneity in cluster randomized crossover designs

X Wang, X Chen, KS Goldfeld… - Statistical Methods in …, 2024 - journals.sagepub.com
<? show [AQ ID= GQ2 POS=-12pt]?><? show [AQ ID= GQ4 POS= 2pt]?><? show [AQ ID=
GQ5 POS= 14pt]?> The cluster randomized crossover design has been proposed to improve …

Optimal designs using generalized estimating equations in cluster randomized crossover and stepped wedge trials

J Liu, F Li - Statistical Methods in Medical Research, 2024 - journals.sagepub.com
<? show [AQ ID= GQ2 POS=-12pt]?><? show [AQ ID= GQ4 POS= 4pt]?><? show [AQ ID=
GQ5 POS= 12pt]?> Cluster randomized crossover and stepped wedge cluster randomized …

A tutorial on conducting sample size and power calculations for detecting treatment effect heterogeneity in cluster randomized trials

MR Baumann, M Taljaard, PJ Heagerty… - arxiv preprint arxiv …, 2025 - arxiv.org
Cluster-randomized trials (CRTs) are a well-established class of designs for evaluating large-
scale, community-based research questions. An essential task in planning these trials is …

Power calculation for cross-sectional stepped wedge cluster randomized trials with a time-to-event endpoint

MM Ryan, D Esserman, M Taljaard, F Li - arxiv preprint arxiv:2312.13097, 2023 - arxiv.org
A popular design choice in public health and implementation science research, stepped
wedge cluster randomized trials (SW-CRTs) are a form of randomized trial whereby clusters …