Nanomedicines improve drug bioavailability, the dose–response relationship, targeting
ability, efficacy and safety compared to conventional freely administered drugs …

Photodynamic therapy (PDT) with selectivity and security has been widely acknowledged as
a promising therapeutic option for cancer treatment. With the swift blossom of phototherapy …

Microbial synthesis of valuable hemoproteins has become a popular research topic, and
Pichia pastoris is a versatile platform for the industrial production of recombinant proteins …

Compared with traditional photodynamic therapy (PDT), ultrasound (US) triggered
sonodynamic therapy (SDT) has a wide application prospect in tumor therapy because of its …

Despite significant achievements in the understanding and treatment of cancer, it remains a
major burden. Traditional therapeutic approaches based on the 'one-size-fits-all'paradigm …

Increasing evidences show the clinical significance of the interaction between hypoxia and
immune in clear cell renal cell carcinoma (ccRCC) microenvironment. However, reliable …

Photodynamic therapy (PDT) has been extensively investigated for cancer treatment by
virtue of singlet oxygen-induced oxidative damage to tumors. Nevertheless, the therapeutic …

Tumor hypoxia drives resistance to many cancer therapies, including radiotherapy and
chemotherapy. Methods that increase tumor oxygen pressures, such as hyperbaric oxygen …

Hemoglobin (Hb)-based oxygen carriers (HBOCs) are being developed as artificial red
blood cell (RBC) substitutes for use in transfusion medicine. Unfortunately, prior generations …

Hypoxia, as a distinctive feature of tumors, is closely related to tumor recurrence, metastasis,
and treatment resistance. Metal–organic framework (MOF) exhibits an increasing number of …