Engineered nanoparticles for cancer vaccination and immunotherapy
Conspectus The immune system has evolved over time to protect the host from foreign
microorganisms. Activation of the immune system is predicated on a distinction between self …
microorganisms. Activation of the immune system is predicated on a distinction between self …
Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …
Non-spherical micro-and nanoparticles for drug delivery: Progress over 15 years
Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …
biological outcome. In this review, we analyze the field of particle shape as it shifts from …
Injectable hydrogels for personalized cancer immunotherapies
The field of cancer immunotherapy has shown significant growth, and researchers are now
focusing on effective strategies to enhance and prolong local immunomodulation. Injectable …
focusing on effective strategies to enhance and prolong local immunomodulation. Injectable …
Tuning the fluidity and protein corona of ultrasound-responsive liposomal nanovaccines to program T cell immunity in mice
Inducing high levels of antigen-specific CD8α+ T cells in the tumor is beneficial for cancer
immunotherapy, but achieving this in a safe and effective manner remains challenging …
immunotherapy, but achieving this in a safe and effective manner remains challenging …
Nanodiscs: Game changer nano-therapeutics and structural biology tools
In recent years, engineering biocompatible HDL nanodiscs has garnered a great interest
with wide applications for for both drug delivery and structural biology. In this review, we …
with wide applications for for both drug delivery and structural biology. In this review, we …
[HTML][HTML] Nano-bio interfaces effect of two-dimensional nanomaterials and their applications in cancer immunotherapy
The field of two-dimensional (2D) nanomaterial-based cancer immunotherapy combines
research from multiple subdisciplines of material science, nano-chemistry, in particular nano …
research from multiple subdisciplines of material science, nano-chemistry, in particular nano …
Synthesis of erythrocyte nanodiscs for bacterial toxin neutralization
Nanodiscs are a compelling nanomedicine platform due to their ultrasmall size and distinct
disc shape. Current nanodisc formulations are made primarily with synthetic lipid bilayers …
disc shape. Current nanodisc formulations are made primarily with synthetic lipid bilayers …
Vaccine nanodiscs plus polyICLC elicit robust CD8+ T cell responses in mice and non-human primates
Conventional cancer vaccines based on soluble vaccines and traditional adjuvants have
produced suboptimal therapeutic efficacy in clinical trials. Thus, there is an urgent need for …
produced suboptimal therapeutic efficacy in clinical trials. Thus, there is an urgent need for …
Albumin-binding lipid-aptamer conjugates for cancer immunoimaging and immunotherapy
L Tian, M Shao, Y Gong, Y Chao, T Wei, K Yang… - Science China …, 2022 - Springer
Monitoring dynamic changes in tumor immune markers are essential for predicting the
therapeutic responses of tumors to immunotherapy, as well as other traditional therapies …
therapeutic responses of tumors to immunotherapy, as well as other traditional therapies …