The objective of this review was to compare and contrast the physiological and metabolic
profiles of rodent white adipose fat pads with white adipose fat depots in humans. Human fat …

The growth hormone receptor (GHR), although most well known for regulating growth, has
many other important biological functions including regulating metabolism and controlling …

The ability of growth hormone (GH) to induce adipose tissue lipolysis has been known for
over five decades; however, the molecular mechanisms that mediate this effect and the …

The important role of GH in the control of mammalian longevity was first deduced from
extended longevity of mice with genetic GH deficiency (GHD) or GH resistance. Mice with …

Considered the definitive source in its field for over 35 years, Endocrinology: Adult and
Pediatric, has been thoroughly updated to reflect today's recent advances in adult and …

Adipocytes are the defining cell type of adipose tissue. Once considered a passive
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …

In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …

Obesity has become one of the most common medical problems in developed countries,
and this disorder is associated with high incidences of hypertension, dyslipidaemia …

GH is an important regulator of body growth and composition as well as numerous other
metabolic processes. In particular, liver plays a key role in the GH/IGF-I axis, because the …

Weight loss triggers important metabolic responses to conserve energy, especially via the
fall in leptin levels. Consequently, weight loss becomes increasingly difficult with weight …