Biological systems are composed of heterogeneous populations of cells that
intercommunicate to form a functional living tissue. Biological function varies greatly across …

Label-free molecular imaging techniques such as matrix-assisted laser desorption ionization
mass spectrometry imaging (MALDI-MSI) enable the direct and simultaneous map** of …

Recently, a novel technology was published, utilizing the strengths of matrix-assisted laser
desorption/ionization (MALDI) mass spectrometry imaging (MSI) and immunohistochemistry …

Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

Matrix-assisted laser desorption and ionization (MALDI) mass spectrometry (MS) is an
indispensable tool in modern lipid research since it is fast, sensitive, tolerates sample …

Mass spectrometry imaging is a technique uniquely suited to localize and identify lipids in a
tissue sample. Using an atmospheric pressure (AP-) matrix-assisted laser desorption …

Significant advances in mass spectrometry imaging (MSI) have pushed the boundaries in
obtaining spatial information and quantification in biological samples. Quantitative MSI …

Mass spectrometry imaging (MSI) has accelerated our understanding of lipid metabolism
and spatial distribution in tissues and cells. However, few MSI studies have approached lipid …

Metabolomics has evolved as a discipline from a discovery and functional genomics tool,
and is now a cornerstone in the era of big data-driven precision medicine. Sample …

Cells often adopt different phenotypes, dictated by tissue-specific or local signals such as
cell-cell and cell-matrix contacts or molecular micro-environment. This holds in extremis for …