Lysophosphatidic acid (LPA) is an abundant bioactive phospholipid, with multiple functions
both in development and in pathological conditions. Here, we review the literature about the …

Lysophosphatidic acid (LPA) is a small ubiquitous lipid found in vertebrate and
nonvertebrate organisms that mediates diverse biological actions and demonstrates …

Lysophosphatidic acid (LPA) is a small, ubiquitous phospholipid that acts as an extracellular
signaling molecule by binding to and activating at least five known G protein–coupled …

Lysophospholipids encompass a diverse range of small, membrane‐derived phospholipids
that act as extracellular signals. The signalling properties are mediated by 7 …

Fingolimod is the first oral disease-modifying therapy approved for relapsing forms of
multiple sclerosis (MS). Following phosphorylation in vivo, the active agent, fingolimod …

Deregulated lipid metabolism may be of particular importance for CNS injuries and
disorders, as this organ has the highest lipid concentration next to adipose tissue …

Lysophosphatidic acid (LPA), a water-soluble phospholipid, has gained significant attention
in recent years since the discovery that it acts as a potent signaling molecule with wide …

Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), two of the best-studied
lysophospholipids, are known to influence diverse biological events, including organismal …

First seen as a storage organ, the white adipose tissue (WAT) is now considered as an
endocrine organ. WAT can produce an array of bioactive factors known as adipokines acting …

Diacylglycerol (DAG) is an important lipid that is both an intermediate in lipid biosynthetic
pathways and can act as a signaling lipid. The majority of signaling DAG is generated by …