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Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management
TS Jensen, P Karlsson, SS Gylfadottir, ST Andersen… - Brain, 2021 - academic.oup.com
Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …
Advances in screening, early diagnosis and accurate staging of diabetic neuropathy
J Carmichael, H Fadavi, F Ishibashi… - Frontiers in …, 2021 - frontiersin.org
The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …
Mechanisms of diabetic complications
It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …
required, but also for its major complications, affecting both small and large blood vessels …
Corneal nerves in health and disease
MA Al-Aqaba, VK Dhillon, I Mohammed… - Progress in retinal and …, 2019 - Elsevier
The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …
maintain transparency and contribute to corneal health by mediating tear secretion and …
In vivo confocal microscopy of corneal nerves in health and disease
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …
Diabetic retinopathy and diabetic macular oedema pathways and management: UK Consensus Working Group
WM Amoaku, F Ghanchi, C Bailey, S Banerjee… - Eye, 2020 - nature.com
The management of diabetic retinopathy (DR) has evolved considerably over the past
decade, with the availability of new technologies (diagnostic and therapeutic). As such, the …
decade, with the availability of new technologies (diagnostic and therapeutic). As such, the …
Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice
SAJ Trammell, BJ Weidemann, A Chadda, MS Yorek… - Scientific reports, 2016 - nature.com
Abstract Male C57BL/6J mice raised on high fat diet (HFD) become prediabetic and develop
insulin resistance and sensory neuropathy. The same mice given low doses of …
insulin resistance and sensory neuropathy. The same mice given low doses of …
Painful and painless diabetic neuropathies: what is the difference?
P Shillo, G Sloan, M Greig, L Hunt, D Selvarajah… - Current diabetes …, 2019 - Springer
Abstract Purpose of Review The prevalence of diabetes mellitus and its chronic
complications are increasing to epidemic proportions. This will unfortunately result in …
complications are increasing to epidemic proportions. This will unfortunately result in …
New perspective in diabetic neuropathy: from the periphery to the brain, a call for early detection, and precision medicine
H Yang, G Sloan, Y Ye, S Wang, B Duan… - Frontiers in …, 2020 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …
Studying human nociceptors: from fundamentals to clinic
SJ Middleton, AM Barry, M Comini, Y Li, PR Ray… - Brain, 2021 - academic.oup.com
Chronic pain affects one in five of the general population and is the third most important
cause of disability-adjusted life-years globally. Unfortunately, treatment remains inadequate …
cause of disability-adjusted life-years globally. Unfortunately, treatment remains inadequate …