Background Dilated cardiomyopathy (DCM) is the most common cardiac disease in large
breed dogs and is inherited in Doberman Pinschers with a high prevalence (58%). Objective …

Dilated cardiomyopathy (DCM) has been in the literature and news because of the recent
opinion-based journal articles and public releases by regulatory agencies. DCM is …

Background: Dilated cardiomyopathy is common in dogs. This form of cardiomyopathy is the
main cause of death due to heart disease in dogs. Death can occur suddenly in clinically …

Sudden death is one of the most common causes of death in humans in Western countries.
Approximately 85% of these cases are of cardiac origin. In dogs and cats, sudden cardiac …

Biomarkers are quantitative indicators of biological processes performed by an organ or
system. In recent years, natriuretic peptides (NPs) have emerged as important tools in the …

Atrial fibrillation (AF) in congestive heart failure (CHF) is associated with a high risk of
mortality and shorter survival times in human and veterinary medicine. A retrospective …

Comparative and translation medicine is of particular value within the field of inherited
cardiomyopathies. Despite massive advances in understanding the functional role of …

Background Echocardiography and 24‐hour ECG are the gold standard tests to diagnose
dilated cardiomyopathy (DCM) in Doberman Pinschers (DP), but myocardial damage might …

Objectives To assess the diagnostic accuracy of two cardiac biomarker assays (N‐terminal
pro‐BNP, Troponin I) in detecting dilated cardiomyopathy in Dobermanns. Materials and …

Abstract Aims Aptamer BC 007, a 15‐mer single‐strand DNA oligonucleotide (5'‐
GGTTGGTGTGGTTGG‐3'), was developed to neutralize functional autoantibodies that bind …