Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …

ABSTRACT RNA interference (RNAi) is an ancient biological mechanism used to defend
against external invasion. It theoretically can silence any disease-related genes in a …

Wound dressing with the capacities of antioxidation, antiinflammation, and efficient
angiogenesis induction is expected for effectively promoting wound healing. Herein, a novel …

Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …

RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …

Repair of large bone defects represents a major challenge for orthopedic surgeons. The
newly formed microvessels inside grafts play a crucial role in successful bone tissue …

Gene vectors are nucleic acids that carry genetic materials or gene editing devices into cells
to exert the sustained production of therapeutic proteins or to correct erroneous genes of the …

Extracellular vesicles (EVs), including exosomes, with nanoscale sizes, biological origins,
various functions, and unique lipid and protein compositions have been introduced as …

Exosomes are bilayer membrane-coated extracellular vesicles measuring between 40 and
100 nm in diameter. As a natural carrier, exosomes have the advantages of low …