Fruit and vegetables (F&V) have been a cornerstone of healthy dietary recommendations;
the 2015–2020 US Dietary Guidelines for Americans recommend that F&V constitute one …

The aging population is expanding, as is the prevalence of age-related cognitive decline
(ARCD). Of the several risk factors that predict the onset and progression of ARCD, 2 …

Background and Objectives Serum antioxidant vitamins and carotenoids may protect against
neurodegeneration with age. We examined associations of these nutritional biomarkers with …

Carotenoid compounds are ubiquitous in nature, providing the characteristic colouring of
many algae, bacteria, fruits and vegetables. They are a critical component of the human diet …

Oxidative stress plays an important role in the development of Alzheimer's disease (AD). The
purpose of this study was to investigate the protective effects of lutein, a carotenoid with …

Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …

Plant breeding has developed corn genotypes with grain higher in levels of carotenoids.
Dietary consumption of specific carotenoids by humans has been associated with improved …

Aging is considered the major risk factor for most chronic disorders. Oxidative stress and
chronic inflammation are two major contributors for cellular senescence, downregulation of …

Background Lutein and zeaxanthin are fat-soluble, dietary carotenoids with high
concentrations in human brain tissue. There have been a number studies confirming an …

Alzheimer's disease (AD) is characterized by, among other things, dementia and a decline in
cognitive performance. In AD, dementia has neurodegenerative features and starts with mild …