Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits

A Caspi, AR Hariri, A Holmes, R Uher… - American journal of …, 2010 - psychiatryonline.org
Evidence of marked variability in response among people exposed to the same
environmental risk implies that individual differences in genetic susceptibility might be at …

Empathy as a “risky strength”: A multilevel examination of empathy and risk for internalizing disorders

EB Tone, EC Tully - Development and psychopathology, 2014 - cambridge.org
Learning to respond to others' distress with well-regulated empathy is an important
developmental task linked to positive health outcomes and moral achievements. However …

Childhood posttraumatic stress disorder

KE Fletcher - Child psychopathology, 1996 - books.google.com
The unpredictable nature of many catastrophic events makes it difficult to determine the
number of children each year who are exposed to traumatic events. Between 6% and 7% of …

Neurobiological mechanisms of early life adversity, blunted stress reactivity and risk for addiction

M al'Absi, AT Ginty, WR Lovallo - Neuropharmacology, 2021 - Elsevier
Blunted stress reactivity resulting from early exposure to stress during childhood and
adolescence may increase vulnerability to addiction. Early life adversity (ELA) affects brain …

Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors

D Suri, CM Teixeira, MKC Cagliostro… - …, 2015 - nature.com
Abstract Development passes through sensitive periods, during which plasticity allows for
genetic and environmental factors to exert indelible influence on the maturation of the …

'Negativity bias' in risk for depression and anxiety: Brain–body fear circuitry correlates, 5-HTT-LPR and early life stress

LM Williams, JM Gatt, PR Schofield, G Olivieri… - Neuroimage, 2009 - Elsevier
The INTEGRATE Model draws on the framework of 'integrative neuroscience'to bring
together brain–body and behavioral concepts of emotion, thinking and feeling and their …

Genetic component of noise sensitivity

M Heinonen-Guzejev, HS Vuorinen… - Twin Research and …, 2005 - cambridge.org
We investigated the genetic component of noise sensitivity using a twin-study design. The
study sample consisted of 573 same-sexed twin pairs from the Finnish Twin Cohort. The 131 …

The genetics of mood disorders

JYF Lau, TC Eley - Annual review of clinical psychology, 2010 - annualreviews.org
Studying the genetics of mood disorders has never been more exciting. We have moved
rapidly from establishing the genetic basis of depression to asking questions about how …

Genetics of emotion

L Bevilacqua, D Goldman - Trends in cognitive sciences, 2011 - cell.com
Emotion is critical to most aspects of human behavior, and individual differences in systems
recruited to process emotional stimuli, expressed as variation in emotionality, are …

The impact of adverse life events and the serotonin transporter gene promoter polymorphism on the development of eating disorder symptoms

K Akkermann, K Kaasik, E Kiive, N Nordquist… - Journal of psychiatric …, 2012 - Elsevier
Adverse life events have been shown to predict weight fluctuations and dietary restraint, as
well as eating disorders during adolescence or early adulthood. Since the s-allele carriers of …