From imbalance to impairment: the central role of reactive oxygen species in oxidative stress-induced disorders and therapeutic exploration

S Afzal, AS Abdul Manap, A Attiq… - Frontiers in …, 2023‏ - frontiersin.org
Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …

Role of oxidative stress in male infertility: an updated review

AT Alahmar - Journal of human reproductive sciences, 2019‏ - journals.lww.com
Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight

T Hussain, M Kandeel, E Metwally, G Murtaza… - Frontiers in …, 2023‏ - frontiersin.org
Male infertility is a widely debated issue that affects males globally. There are several
mechanisms involved. Oxidative stress is accepted to be the main contributing factor, with …

Oxidative stress and male infertility

S Bisht, M Faiq, M Tolahunase, R Dada - Nature Reviews Urology, 2017‏ - nature.com
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …

Review on the role of glutathione on oxidative stress and infertility

O Adeoye, J Olawumi, A Opeyemi… - JBRA assisted …, 2018‏ - pmc.ncbi.nlm.nih.gov
Infertility is a global health problem and it is one of the most stressful conditions amongst
married couples. Even though not lethal, it has been described as a radical life changing …

[HTML][HTML] Male infertility testing: reactive oxygen species and antioxidant capacity

EY Ko, ES Sabanegh Jr, A Agarwal - Fertility and sterility, 2014‏ - Elsevier
Reactive oxygen species (ROS) are an integral component of sperm developmental
physiology, capacitation, and function. Elevated ROS levels, from processes such as …

The impact of bisphenol A on fertility, reproductive system, and development: a review of the literature

E Matuszczak, MD Komarowska… - International journal …, 2019‏ - Wiley Online Library
Bisphenol A (BPA) has been used since the 1950s, in food packaging, industrial materials,
dental sealants, and personal hygiene products. Everyone is exposed to BPA through skin …

[HTML][HTML] Effect of folic acid and zinc supplementation in men on semen quality and live birth among couples undergoing infertility treatment: a randomized clinical trial

EF Schisterman, LA Sjaarda, T Clemons, DT Carrell… - Jama, 2020‏ - jamanetwork.com
Importance Dietary supplements marketed for male fertility commonly contain folic acid and
zinc based on limited prior evidence for improving semen quality. However, no large-scale …

[HTML][HTML] Role of reactive oxygen species in the pathophysiology of human reproduction

A Agarwal, RA Saleh, MA Bedaiwy - Fertility and sterility, 2003‏ - Elsevier
OBJECTIVE: To summarize the role of reactive oxygen species (ROS) in the
pathophysiology of human reproduction. DESIGN: Review of literature. SETTING: Fertility …

Antioxidant systems and oxidative stress in the testes

RJ Aitken, SD Roman - Molecular mechanisms in spermatogenesis, 2008‏ - Springer
Spermatogenesis is an extremely active replicative process capable of generating approxi
mately 1,000 sperm a second. The high rates of cell division inherent in this process imply …