Software tools for automated transmission electron microscopy
The demand for high-throughput data collection in electron microscopy is increasing for
applications in structural and cellular biology. Here we present a combination of software …
applications in structural and cellular biology. Here we present a combination of software …
Complex relationship between cardiac fibroblasts and cardiomyocytes in health and disease
Cardiac fibroblasts are the primary cell type responsible for deposition of extracellular matrix
in the heart, providing support to the contracting myocardium and contributing to a myriad of …
in the heart, providing support to the contracting myocardium and contributing to a myriad of …
Cardiac optogenetics: a decade of enlightenment
The electromechanical function of the heart involves complex, coordinated activity over time
and space. Life-threatening cardiac arrhythmias arise from asynchrony in these space–time …
and space. Life-threatening cardiac arrhythmias arise from asynchrony in these space–time …
3D co-culture of hiPSC-derived cardiomyocytes with cardiac fibroblasts improves tissue-like features of cardiac spheroids
P Beauchamp, CB Jackson, LC Ozhathil… - Frontiers in molecular …, 2020 - frontiersin.org
Purpose: Both cardiomyocytes and cardiac fibroblasts (CF) play essential roles in cardiac
development, function, and remodeling. Properties of 3D co-cultures are incompletely …
development, function, and remodeling. Properties of 3D co-cultures are incompletely …
Mechanical regulation of gene expression in cardiac myocytes and fibroblasts
The intact heart undergoes complex and multiscale remodelling processes in response to
altered mechanical cues. Remodelling of the myocardium is regulated by a combination of …
altered mechanical cues. Remodelling of the myocardium is regulated by a combination of …
Cardiac mechano-electric coupling: acute effects of mechanical stimulation on heart rate and rhythm
The heart is vital for biological function in almost all chordates, including humans. It beats
continually throughout our life, supplying the body with oxygen and nutrients while removing …
continually throughout our life, supplying the body with oxygen and nutrients while removing …
Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions
J Ariazi, A Benowitz, V De Biasi… - Frontiers in molecular …, 2017 - frontiersin.org
Cell-to-cell communication is essential for the organization, coordination, and development
of cellular networks and multi-cellular systems. Intercellular communication is mediated by …
of cellular networks and multi-cellular systems. Intercellular communication is mediated by …
The heterocellular heart: identities, interactions, and implications for cardiology
The heterocellular nature of the heart has been receiving increasing attention in recent
years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes …
years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes …
Role of connexin 43 in different forms of intercellular communication–gap junctions, extracellular vesicles and tunnelling nanotubes
TM Ribeiro-Rodrigues… - Journal of cell …, 2017 - journals.biologists.com
Communication is important to ensure the correct and efficient flow of information, which is
required to sustain active social networks. A fine-tuned communication between cells is vital …
required to sustain active social networks. A fine-tuned communication between cells is vital …
Electroimmunology and cardiac arrhythmia
Conduction disorders and arrhythmias remain difficult to treat and are increasingly prevalent
owing to the increasing age and body mass of the general population, because both are risk …
owing to the increasing age and body mass of the general population, because both are risk …