Inflammatory Arthritis is characterized by synovial proliferation, neovascularization and
leukocyte extravasation leading to joint destruction and functional disability. Efficiency of …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

Angiogenesis and inflammation are closely integrated processes in osteoarthritis (OA) and
may affect disease progression and pain. Inflammation can stimulate angiogenesis, and …

Cellular senescence is a state of stable proliferation arrest of cells. The senescence pathway
has many beneficial effects and is seen to be activated in damaged/stressed cells, as well as …

Synovial proliferation, neovascularization and leukocyte extravasation transform the
normally acellular synovium into an invasive tumour-like'pannus'. The highly dysregulated …

Oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis.
Reactive oxygen species (ROS) produced in the course of cellular oxidative …

Increased vascular endothelial growth factor (VEGF) levels are associated with osteoarthritis
(OA) progression. Indeed, VEGF appears to be involved in OA‐specific pathologies …

Activation of endothelium and immune cells is fundamental to the initiation of autoimmune
diseases such as rheumatoid arthritis (RA), and it results in trans-endothelial cell migration …

Rheumatoid arthritis (RA) is a chronic inflammatory disease, associated with inflammation of
the synovial tissue lining joints and tendons, which leads to degradation of underlying …

Angiogenesis or formation of new blood vessels from preexisting vasculature is a key
process in some physiological conditions such as wound healing, growth, and action of …