Current trends in polymer microneedle for transdermal drug delivery
Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …
Microneedles for painless transdermal immunotherapeutic applications
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …
the treatment of various diseases. However, owing to the dynamic nature of the immune …
[HTML][HTML] Recent advances of microneedles for biomedical applications: drug delivery and beyond
J Yang, X Liu, Y Fu, Y Song - Acta Pharmaceutica Sinica B, 2019 - Elsevier
The microneedle (MN), a highly efficient and versatile device, has attracted extensive
scientific and industrial interests in the past decades due to prominent properties including …
scientific and industrial interests in the past decades due to prominent properties including …
3D printed microneedles for anticancer therapy of skin tumours
In this study, novel 3D printed polymeric microneedle arrays were fabricated for enhanced
cisplatin delivery to A-431 epidermoid skin tumours for cancer treatment. The microneedles …
cisplatin delivery to A-431 epidermoid skin tumours for cancer treatment. The microneedles …
Microneedles: a new generation vaccine delivery system
Transdermal vaccination route using biodegradable microneedles is a rapidly progressing
field of research and applications. The fear of painful needles is one of the primary reasons …
field of research and applications. The fear of painful needles is one of the primary reasons …
Chemical strategies to boost cancer vaccines
WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …
Recent advances in microneedles-based drug delivery device in the diagnosis and treatment of cancer
V Singh, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
Microneedles are unique, novel and an effective approach designed to deliver therapeutic
agents and immunobiologicals in several diseases. These tiny needle patches are designed …
agents and immunobiologicals in several diseases. These tiny needle patches are designed …
Dissolvable polymer microneedles for drug delivery and diagnostics
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …
a wide selection of active compounds into the skin. To provide an effective therapeutic …
[HTML][HTML] Trends in drug-and vaccine-based dissolvable microneedle materials and methods of fabrication
Microneedle patches, also called microarray patches (MAP), are an emerging technology for
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …
Methods to improve the immunogenicity of plasmid DNA vaccines
DNA vaccines have emerged as innovative approaches that have great potential to
overcome the limitations of current conventional vaccines. Plasmid DNA vaccines are often …
overcome the limitations of current conventional vaccines. Plasmid DNA vaccines are often …