Understanding bacterial biofilms: From definition to treatment strategies

A Zhao, J Sun, Y Liu - Frontiers in cellular and infection microbiology, 2023 - frontiersin.org
Bacterial biofilms are complex microbial communities encased in extracellular polymeric
substances. Their formation is a multi-step process. Biofilms are a significant problem in …

Aptamers against pathogenic bacteria: selection strategies and apta-assay/aptasensor application for food safety

M Liu, F Yue, Q Kong, Z Liu, Y Guo… - Journal of Agricultural …, 2022 - ACS Publications
Pathogenic bacteria are primarily kinds of detrimental agents that cause mankind illness via
contaminated food with traits of multiple types, universality, and low content. In view of the …

Novel strategies to combat bacterial biofilms

F Hemmati, MA Rezaee, S Ebrahimzadeh… - Molecular …, 2021 - Springer
Biofilms are considered as a severe problem in the treatment of bacterial infections; their
development causes some noticeable resistance to antibacterial agents. Biofilms are …

[HTML][HTML] Current strategies for monitoring and controlling bacterial biofilm formation on medical surfaces

X Wang, C Chen, J Hu, C Liu, Y Ning, F Lu - … and Environmental Safety, 2024 - Elsevier
Biofilms, intricate microbial communities that attach to surfaces, especially medical devices,
form an exopolysaccharide matrix, which enables bacteria to resist environmental pressures …

Assessment of the growth inhibition and anti-biofilm activity of aptamer (PmA2G02) against Proteus mirabilis 1429T

R Elumalai, A Vishwakarma, A Balakrishnan… - Research in …, 2024 - Elsevier
Proteus mirabilis is known to cause Catheter-associated urinary tract infections (CAUTIs),
which exhibit virulence factors linked to forming biofilms. Aptamers have recently been …

[HTML][HTML] Aptamer-based therapy for fighting biofilm-associated infections

AM Sousa, D Ferreira, LR Rodrigues… - Journal of Controlled …, 2024 - Elsevier
Biofilms are key players in the pathogenesis of most of chronic infections associated with
host tissue or fluids and indwelling medical devices. These chronic infections are hard to be …

Applications and Challenges of Bacteriostatic Aptamers in the Treatment of Common Pathogenic Bacteria Infections

D Li, Y Su, J Li, R Liu, B Fang, J He, W Xu… - …, 2023 - ACS Publications
The continuous evolution and spread of common pathogenic bacteria is a major challenge
in diagnosis and treatment with current biotechnology and modern molecular medicine. To …

Aptamers: precision tools for diagnosing and treating infectious diseases

S Sujith, R Naresh, BU Srivisanth… - Frontiers in Cellular …, 2024 - frontiersin.org
Infectious diseases represent a significant global health challenge, with bacteria, fungi,
viruses, and parasitic protozoa being significant causative agents. The shared symptoms …

[HTML][HTML] Selection of streptococcal glucan-binding protein C specific DNA aptamers to inhibit biofilm formation

Á Harkai, YK Beck, A Tory, T Mészáros - International Journal of Biological …, 2025 - Elsevier
Streptococcus mutans is a commensal oral bacterium, yet its capacity for extensive biofilm
formation is a major contributor to dental caries. This study presents a novel biofilm inhibition …

[HTML][HTML] Novel Aptamer Strategies in Combating Bacterial Infections: From Diagnostics to Therapeutics

Z Ye, H Chen, H Weinans, B van der Wal, JL Rios - Pharmaceutics, 2024 - mdpi.com
Bacterial infections and antimicrobial resistance are posing substantial difficulties to the
worldwide healthcare system. The constraints of conventional diagnostic and therapeutic …