Cellular metabolism orchestrates the intricate use of tissue fuels for catabolism and
anabolism to generate cellular energy and structural components. The emerging field of …

Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

Resident tissue macrophages (RTMs) have a broad spectrum of immune-and non-immune-
related tissue-supporting activities. The roots of this heterogeneity and versatility are only …

Inflammation is a hallmark of virtually all liver diseases, such as liver cancer, fibrosis,
nonalcoholic steatohepatitis, alcoholic liver disease, and cholangiopathies. Liver …

Macrophages are critical for innate immune defense and also control organ homeostasis in
a tissue-specific manner. They provide a fitting model to study the impact of ontogeny and …

Tumor-associated macrophages (TAMs) are a major cellular component in the tumor
microenvironment (TME). However, the relationship between the phenotype and metabolic …

Macrophages are immune cells of haematopoietic origin that provide crucial innate immune
defence and have tissue-specific functions in the regulation and maintenance of organ …

Macrophages are distributed in tissues throughout the body and contribute to both
homeostasis and disease. Recently, it has become evident that most adult tissue …

Macrophages are essential components of mammalian tissues. Although historically known
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …

Macrophages reside in essentially all tissues of the body and play key roles in innate and
adaptive immune responses. Distinct populations of tissue macrophages also acquire …