Identification and prioritization of environmental organic pollutants: from an analytical and toxicological perspective

T Ruan, P Li, H Wang, T Li, G Jiang - Chemical Reviews, 2023 - ACS Publications
Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

NORMAN guidance on suspect and non-target screening in environmental monitoring

J Hollender, EL Schymanski, L Ahrens… - Environmental Sciences …, 2023 - Springer
Increasing production and use of chemicals and awareness of their impact on ecosystems
and humans has led to large interest for broadening the knowledge on the chemical status …

Development and application of liquid chromatographic retention time indices in HRMS-based suspect and nontarget screening

R Aalizadeh, NA Alygizakis, EL Schymanski… - Analytical …, 2021 - ACS Publications
There is an increasing need for comparable and harmonized retention times (t R) in liquid
chromatography (LC) among different laboratories, to provide supplementary evidence for …

The next generation blueprint of computational toxicology at the US Environmental Protection Agency

RS Thomas, T Bahadori, TJ Buckley… - Toxicological …, 2019 - academic.oup.com
Abstract The US Environmental Protection Agency (EPA) is faced with the challenge of
efficiently and credibly evaluating chemical safety often with limited or no available toxicity …

Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)

KA Lippa, JJ Aristizabal-Henao, RD Beger, JA Bowden… - Metabolomics, 2022 - Springer
Introduction The metabolomics quality assurance and quality control consortium (mQACC) is
enabling the identification, development, prioritization, and promotion of suitable reference …

Practical application guide for the discovery of novel PFAS in environmental samples using high resolution mass spectrometry

M Strynar, J McCord, S Newton, J Washington… - Journal of Exposure …, 2023 - nature.com
Background The intersection of the topics of high-resolution mass spectrometry (HRMS) and
per-and polyfluoroalkyl substances (PFAS) bring together two disparate and complex …

Defining the scope of exposome studies and research needs from a multidisciplinary perspective

P Zhang, C Carlsten, R Chaleckis… - … science & technology …, 2021 - ACS Publications
The concept of the exposome was introduced over 15 years ago to reflect the important role
that the environment exerts on health and disease. While originally viewed as a call-to-arms …

Suspect and non-targeted screening of chemicals of emerging concern for human biomonitoring, environmental health studies and support to risk assessment: From …

M Pourchet, L Debrauwer, J Klanova, EJ Price… - Environment …, 2020 - Elsevier
Large-scale suspect and non-targeted screening approaches based on high-resolution
mass spectrometry (HRMS) are today available for chemical profiling and holistic …

Critical assessment of the chemical space covered by LC–HRMS non-targeted analysis

T Hulleman, V Turkina, JW O'Brien… - Environmental …, 2023 - ACS Publications
Non-targeted analysis (NTA) has emerged as a valuable approach for the comprehensive
monitoring of chemicals of emerging concern (CECs) in the exposome. The NTA approach …

[HTML][HTML] Sample preparation techniques for suspect and non-target screening of emerging contaminants

P Hajeb, L Zhu, R Bossi, K Vorkamp - Chemosphere, 2022 - Elsevier
The progress in sensitivity and resolution in mass spectrometers in recent years provides the
possibility to detect a broad range of organic compounds in a single procedure. For this …