Abstract Magnesium (Mg 2+) is an essential ion to the human body, playing an instrumental
role in supporting and sustaining health and life. As the second most abundant intracellular …

Neuroprotection for ischemic stroke refers to strategies, applied singly or in combination, that
antagonize the injurious biochemical and molecular events that eventuate in irreversible …

Magnesium plays a fundamental role in many cellular functions, and thus there is increasing
interest in its role in clinical medicine. Although numerous experimental studies indicate …

BACKGROUND: Magnesium is neuroprotective in animal models of stroke, and findings of
small clinical pilot trials suggest potential benefit in people. We aimed to test whether …

Magnesium (Mg) deficiency commonly occurs in critical illness and correlates with a higher
mortality and worse clinical outcome in the intensive care unit (ICU). Magnesium has been …

After decades of research, schizophrenia and related psychotic disorders are still among the
most debilitating disorders in medicine. The chronic illness course in most individuals …

It has long been accepted that high concentrations of glutamate can destroy neurons, and
this is the basis of the theory of excitotoxicity during brain injury such as stroke. Glutamate N …

Stroke is one of the leading causes of death and disability worldwide. Current treatment
strategies for ischemic stroke primarily focus on reducing the size of ischemic damage and …

Stroke is a major cause of both death and disability. However, there are no pharmacological
treatments used in most countries other than recombinant tissue plasminogen activator, a …

Acute ischaemic stroke is a major health problem with no effective treatments apart from the
thrombolytic recombinant tissue plasminogen activator (rt-PA), which must be given within …