Myocardial ischemia-reperfusion injury: a neglected therapeutic target

DJ Hausenloy, DM Yellon - The Journal of clinical …, 2013 - Am Soc Clin Investig
Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In
patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and …

The assessment of endothelial function: from research into clinical practice

AJ Flammer, T Anderson, DS Celermajer, MA Creager… - Circulation, 2012 - Am Heart Assoc
The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function

RJ Kim, DS Fieno, TB Parrish, K Harris, EL Chen… - Circulation, 1999 - Am Heart Assoc
Background—Contrast MRI enhancement patterns in several pathophysiologies resulting
from ischemic myocardial injury are controversial or have not been investigated. We …

Coronary microvascular dysfunction

PG Camici, F Crea - New England Journal of Medicine, 2007 - Mass Medical Soc
This review discusses the pathogenesis and management of coronary microvascular
dysfunction. Factors to consider in clinical management are the cause of the dysfunction and …

Modified Look‐Locker inversion recovery (MOLLI) for high‐resolution T1 map** of the heart

DR Messroghli, A Radjenovic… - … in Medicine: An …, 2004 - Wiley Online Library
A novel pulse sequence scheme is presented that allows the measurement and map** of
myocardial T1 in vivo on a 1.5 Tesla MR system within a single breath‐hold. Two major …

ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation …

WG Hundley, DA Bluemke, JP Finn, SD Flamm… - Journal of the American …, 2010 - jacc.org
The writing committee consisted of acknowledged experts in the field of CMR, as well as a
liaison from the ACCF Task Force on Clinical ECDs, the oversight group for this document …

ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on 'coronary microvascular dysfunction in cardiovascular disease'

T Padro, O Manfrini, R Bugiardini, J Canty… - Cardiovascular …, 2020 - academic.oup.com
Although myocardial ischaemia usually manifests as a consequence of atherosclerosis-
dependent obstructive epicardial coronary artery disease, a significant percentage of …

Myocardial no-reflow in humans

G Niccoli, F Burzotta, L Galiuto, F Crea - Journal of the American College of …, 2009 - jacc.org
In a variable proportion of patients presenting with ST-segment elevation myocardial
infarction, ranging from 5% to 50%, primary percutaneous coronary intervention achieves …

Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial …

S De Waha, MR Patel, CB Granger… - European heart …, 2017 - academic.oup.com
Aims Microvascular obstruction (MVO) is the underlying cause for the no-reflow
phenomenon in ST-segment elevation myocardial infarction (STEMI). The association …

Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report

DJ Pennell, UP Sechtem, CB Higgins… - European heart …, 2004 - academic.oup.com
Cardiovascular magnetic resonance (CMR) is established in clinical practice for the
diagnosis and management of diseases of the cardiovascular system. However, current …