Neuronal activity in the brain gives rise to transmembrane currents that can be measured in
the extracellular medium. Although the major contributor of the extracellular signal is the …

Neural recording electrode technologies have contributed considerably to neuroscience by
enabling the extracellular detection of low-frequency local field potential oscillations and …

This book provides eloquent support for the idea that spontaneous neuron activity, far from
being mere noise, is actually the source of our cognitive abilities. In a sequence of" cycles," …

Although fluorescence microscopy permeates all of cell and molecular biology, most
biologists have little experience with the underlying photophysical phenomena …

Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from
neurophysiology, computer science, and engineering in an effort to establish real-time …

Major depressive disorder is a serious mental disorder that profoundly affects an individual's
quality of life. Although the aetiologies underlying this disorder remain unclear, an …

The brain is complex and dynamic. The spatial scales of interest to the neurobiologist range
from individual synapses (∼ 1 μm) to neural circuits (centimeters); the timescales range from …

Nanoelectronic devices offer substantial potential for interrogating biological systems,
although nearly all work has focused on planar device designs. We have overcome this …

Elucidation of the neural substrates underlying complex animal behaviors depends on
precise activity control tools, as well as compatible readout methods. Recent developments …

The biomedical sciences have recently undergone revolutionary change, due to the ability to
digitize and store large data sets. In neuroscience, the data sources include measurements …