Decorated bacteria and the application in drug delivery

F Wu, J Liu - Advanced Drug Delivery Reviews, 2022 - Elsevier
The use of living bacteria either as therapeutic agents or drug carriers has shown great
potential in treating a multitude of intractable diseases. However, cells are often fragile to …

Chemical reporters for bacterial glycans: development and applications

N Banahene, HW Kavunja, BM Swarts - Chemical reviews, 2021 - ACS Publications
Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

Peptidoglycan muropeptides: release, perception, and functions as signaling molecules

O Irazoki, SB Hernandez, F Cava - Frontiers in microbiology, 2019 - frontiersin.org
Peptidoglycan (PG) is an essential molecule for the survival of bacteria, and thus, its
biosynthesis and remodeling have always been in the spotlight when it comes to the …

Killing of Staphylococcus aureus persisters by a multitarget natural product chrysomycin A

J Jia, M Zheng, C Zhang, B Li, C Lu, Y Bai, Q Tong… - Science …, 2023 - science.org
Staphylococcus aureus poses a severe public health problem as one of the vital causative
agents of healthcare-and community-acquired infections. There is a globally urgent need for …

AIEgens for microorganism‐related visualization and therapy

Z Ye, W He, Z Zhang, Z Qiu, Z Zhao… - Interdisciplinary …, 2023 - Wiley Online Library
Humans and bacteria have always been closely related. However, pathogenic bacteria and
drug‐resistant bacteria pose a certain threat to human life and health. On the other hand …

[HTML][HTML] Biofilm microenvironment-responsive nanotheranostics for dual-mode imaging and hypoxia-relief-enhanced photodynamic therapy of bacterial infections

W **u, S Gan, Q Wen, Q Qiu, S Dai, H Dong, Q Li… - Research, 2020 - spj.science.org
The formation of bacterial biofilms closely associates with infectious diseases. Until now,
precise diagnosis and effective treatment of bacterial biofilm infections are still in great need …

Visualization and in situ ablation of intracellular bacterial pathogens through metabolic labeling

F Hu, G Qi, Kenry, D Mao, S Zhou, M Wu… - Angewandte Chemie …, 2020 - Wiley Online Library
Protected by the host cells, the hidden intracellular bacteria are typically difficult to kill by
common antibiotics and cannot be visualized without complex cellular pretreatments …

Bacterial peptidoglycan fragments differentially regulate innate immune signaling

KL Bersch, KE DeMeester, R Zagani, S Chen… - ACS central …, 2021 - ACS Publications
The human innate immune system responds to both pathogen and commensal bacteria at
the molecular level using bacterial peptidoglycan (PG) recognition elements. Traditionally …

Biosynthetic glycan labeling

VM Marando, DE Kim, PJ Calabretta… - Journal of the …, 2021 - ACS Publications
Glycans are ubiquitous and play important biological roles, yet chemical methods for
probing their structure and function within cells remain limited. Strategies for studying other …

Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers

SH Lee, JM Kim, M López-Álvarez, C Wang… - ACS …, 2023 - ACS Publications
Imaging infections in patients is challenging using conventional methods, motivating the
development of positron emission tomography (PET) radiotracers targeting bacteria-specific …