Keratoconus

RB Singh, S Koh, N Sharma, FA Woreta… - Nature Reviews …, 2024 - nature.com
Keratoconus is a progressive eye disorder primarily affecting individuals in adolescence and
early adulthood. The ectatic changes in the cornea cause thinning and cone-like steepening …

Prevalence and risk factors of myopia in young adults: review of findings from the raine study

SSY Lee, DA Mackey - Frontiers in public health, 2022 - frontiersin.org
Myopia tends to develop and progress fastest during childhood, and the age of stabilization
has been reported to be 15–16 years old. Thus, most studies on myopia have centered on …

Incidence and progression of myopia in early adulthood

SSY Lee, G Lingham, PG Sanfilippo… - JAMA …, 2022 - jamanetwork.com
Importance Myopia incidence and progression has been described extensively in children.
However, few data exist regarding myopia incidence and progression in early adulthood …

Enhanced adipose-derived stem cells with IGF-1-modified mRNA promote wound healing following corneal injury

F Yu, D Gong, D Yan, H Wang, N Witman, Y Lu, W Fu… - Molecular Therapy, 2023 - cell.com
The cornea serves as an important barrier structure to the eyeball and is vulnerable to
injuries, which may lead to scarring and blindness if not treated promptly. To explore an …

A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus

AJ Hardcastle, P Liskova, Y Bykhovskaya… - Communications …, 2021 - nature.com
Keratoconus is characterised by reduced rigidity of the cornea with distortion and focal
thinning that causes blurred vision, however, the pathogenetic mechanisms are unknown. It …

Keratoconus epidemiology: A review

JAP Gomes, PF Rodrigues… - Saudi Journal of …, 2022 - journals.lww.com
Keratoconus is an ectatic corneal disease that affects both men and women, usually at a
young age. Risk factors such as eye rubbing, environmental and genetic factors contribute to …

Nutritional and metabolic imbalance in keratoconus

RM Lasagni Vitar, F Bonelli, P Rama, G Ferrari - Nutrients, 2022 - mdpi.com
Keratoconus (KC) is a progressive corneal degeneration characterized by structural
changes consisting of progressive thinning and steepening of the cornea. These alterations …

Different keratoconus definitions can lead to substantial prevalence disparities in population-based studies

H Shabani, BTH van Dooren, MA Meester-Smoor… - Scientific Reports, 2025 - nature.com
This report explores the prevalence of keratoconus in a population-based cohort of adults
aged 40 or older according to ten different definitions. All Rotterdam Study participants with …

Advances in artificial intelligence applications for ocular surface diseases diagnosis

Y Ji, S Liu, X Hong, Y Lu, X Wu, K Li, K Li… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent years, with the rapid development of computer technology, continual optimization
of various learning algorithms and architectures, and establishment of numerous large …

Keratoconus: diagnosis and staging

MW Belin, HS Jang, M Borgstrom - Cornea, 2022 - journals.lww.com
The advent of refractive surgery and corneal cross-linking for ectatic disease has further
highlighted the need to recognize early or subclinical ectatic disease. Historical systems …