Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

The aboveground parts of terrestrial plants are colonized by a variety of microbes that
collectively constitute the phyllosphere microbiota. Decades of pioneering work using …

We introduce BacDrop, a highly scalable technology for bacterial single-cell RNA
sequencing that has overcome many challenges hindering the development of scRNA-seq …

INTRODUCTION Microbial populations display heterogeneous gene expression profiles that
result in phenotypic differences between individual bacteria. This diversity can allow …

Abstract Machine learning is increasingly important in microbiology where it is used for tasks
such as predicting antibiotic resistance and associating human microbiome features with …

Bacteria colonize almost all parts of the human body and can differ significantly. However,
the population level transcriptomics measurements can only describe the average bacteria …

The human intestinal microbiome has coevolved with its host to establish a stable
homeostatic relationship with hallmark features of mutualistic symbioses, yet the mechanistic …

Microbiomes occupy a range of niches and, in addition to having diverse compositions, they
have varied functional roles that have an impact on agriculture, environmental sciences, and …

Microbial culturing and meta-omic profiling technologies have significantly advanced our
understanding of the taxonomic and functional variation of the human microbiome and its …

Clonal bacterial populations rely on transcriptional variation across individual cells to
produce specialized states that increase fitness. Understanding all cell states requires …