Cognition deficits in Parkinson's disease: mechanisms and treatment

C Fang, L Lv, S Mao, H Dong, B Liu - Parkinson's disease, 2020 - Wiley Online Library
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder mainly in middle‐elderly population, which represents diverse nonmotor symptoms …

Parkinson's disease dementia: a neural networks perspective

J Gratwicke, M Jahanshahi, T Foltynie - Brain, 2015 - academic.oup.com
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …

Cognitive impairment in Parkinson's disease: a report from a multidisciplinary symposium on unmet needs and future directions to maintain cognitive health

JG Goldman, BA Vernaleo, R Camicioli… - npj Parkinson's …, 2018 - nature.com
People with Parkinson's disease (PD) and their care partners frequently report cognitive
decline as one of their greatest concerns. Mild cognitive impairment affects approximately 20 …

Cognitive impairment and resting‐state network connectivity in P arkinson's disease

HC Baggio, B Segura, R Sala‐Llonch… - Human brain …, 2015 - Wiley Online Library
The purpose of this work was to evaluate changes in the connectivity patterns of a set of
cognitively relevant, dynamically interrelated brain networks in association with cognitive …

Cognitive decline in Parkinson's disease: the complex picture

R Biundo, L Weis, A Antonini - npj Parkinson's Disease, 2016 - nature.com
Mild cognitive impairment (PD-MCI) and dementia (PDD) are among the most frequent non-
motor symptoms in Parkinson's disease (PD). PD-MCI is six times more likely than age …

Biomarkers for dementia and mild cognitive impairment in Parkinson's disease

M Delgado‐Alvarado, B Gago… - Movement …, 2016 - Wiley Online Library
Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …

Meta-analysis of cognition in Parkinson's disease mild cognitive impairment and dementia progression

ER Wallace, SC Segerstrom, CG van Horne… - Neuropsychology …, 2022 - Springer
Mild cognitive changes, including executive dysfunction, are seen in Parkinson's Disease
(PD). Approximately 30% of individuals with PD develop Parkinson's disease dementia …

Distinct global brain dynamics and spatiotemporal organization of the salience network

T Chen, W Cai, S Ryali, K Supekar, V Menon - PLoS biology, 2016 - journals.plos.org
One of the most fundamental features of the human brain is its ability to detect and attend to
salient goal-relevant events in a flexible manner. The salience network (SN), anchored in …

Uncovering the role of the insula in non-motor symptoms of Parkinson's disease

L Christopher, Y Koshimori, AE Lang, M Criaud… - Brain, 2014 - academic.oup.com
Patients with Parkinson's disease experience a range of non-motor symptoms, including
cognitive impairment, behavioural changes, somatosensory and autonomic disturbances …

Molecular imaging to track Parkinson's disease and atypical parkinsonisms: new imaging frontiers

AP Strafella, NI Bohnen, JS Perlmutter… - Movement …, 2017 - Wiley Online Library
Molecular imaging has proven to be a powerful tool for investigation of parkinsonian
disorders. One current challenge is to identify biomarkers of early changes that may predict …