Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens
J Gao, H Hou, F Gao - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract The ESKAPE (Escherichia coli/E. coli, Staphylococcus aureus/S. aureus, Klebsiella
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …
The antibacterial activity of fluoroquinolone derivatives: An update (2018–2021)
Y Jia, L Zhao - European journal of medicinal chemistry, 2021 - Elsevier
Bacterial infection is amongst the most common diseases in community and hospital
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …
[HTML][HTML] In vitro antimicrobial evaluation, single-point resistance study, and radiosterilization of novel pyrazole incorporating thiazol-4-one/thiophene derivatives as …
HA Mohamed, YA Ammar, GAM Elhagali, HA Eyada… - ACS …, 2022 - ncbi.nlm.nih.gov
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …
attractive cores were initially synthesized using a hybridization approach. All structures were …
Synthesis, characterization, DFT, biological activity evaluation, and molecular docking analysis of new 8-[(2-hydroxynaphthalen-1-yl) diazenyl] naphthalene-1, 3 …
Three novel metal complexes of 2‑hydroxy-1-naphthaldehyde azine (HNANSA) with iron
(III), nickel (II), and copper (II) have been synthesized and characterized. Various analytical …
(III), nickel (II), and copper (II) have been synthesized and characterized. Various analytical …
A comprehensive review of recent advances in the biological activities of 1, 2, 4‐oxadiazoles
OM Hendawy - Archiv der Pharmazie, 2022 - Wiley Online Library
Nitrogen heterocycles play an essential role in medication development. The 1, 2, 4‐
oxadiazole heterocycle has been extensively studied, yielding a large variety of molecules …
oxadiazole heterocycle has been extensively studied, yielding a large variety of molecules …
In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual …
H Ali Mohamed, YA Ammar, G AM Elhagali… - ACS …, 2022 - ACS Publications
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …
attractive cores were initially synthesized using a hybridization approach. All structures were …
Fabrication, structural, DFT, biological and molecular docking studies of Fe (III), Ni (II), and Cu (II) complexes based on Schiff-base derived from benzene-1, 4-diamine …
This study presents the design & comprehensive characterization of three novel metal
complexes derived from a Schiff base compound (H 2 PDN) synthesized from benzene-1, 4 …
complexes derived from a Schiff base compound (H 2 PDN) synthesized from benzene-1, 4 …
New Prospective Insecticidal Agents Based on N‐(arylcarbamothioyl)arylmide Derivatives Against Spodoptera frugiperda: Design, Synthesis, Toxicological …
In this work, a novel series of N‐(arylcarbamothioyl) arylmide) 2–11 were synthesized by
treating One‐Pot three‐multicomponent of Aroyl chloride, ammonium isothiocyanate and …
treating One‐Pot three‐multicomponent of Aroyl chloride, ammonium isothiocyanate and …
Synthesis, X-ray crystallography and antimicrobial activity of 2-cyanoguanidinophenytoin
The optimized synthesis of [5-oxo-4, 4-diphenylimidazolidin-2-ylidene] cyanamide, which is
known as 2-cyanoguanidinophenytoin (CNG-DPH)(3), and (imidazo [4, 5-d] imidazole-2, 5 …
known as 2-cyanoguanidinophenytoin (CNG-DPH)(3), and (imidazo [4, 5-d] imidazole-2, 5 …
Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors
Microbial DNA gyrase is regarded as an outstanding microbial target. Hence, 15 new
quinoline derivatives (5–14) were designed and synthesized. The antimicrobial activity of …
quinoline derivatives (5–14) were designed and synthesized. The antimicrobial activity of …