Alkaloids used as medicines: Structural phytochemistry meets biodiversity—An update and forward look

M Heinrich, J Mah, V Amirkia - Molecules, 2021 - mdpi.com
Selecting candidates for drug developments using computational design and empirical rules
has resulted in a broad discussion about their success. In a previous study, we had shown …

[HTML][HTML] Plant tissue culture as a perpetual source for production of industrially important bioactive compounds

H Chandran, M Meena, T Barupal, K Sharma - Biotechnology reports, 2020 - Elsevier
Plants have been used throughout the world for its medicinal powers since ancient time. The
pharmacological properties of plants are based on their phytochemical components …

A microbial supply chain for production of the anti-cancer drug vinblastine

J Zhang, LG Hansen, O Gudich, K Viehrig… - Nature, 2022 - nature.com
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary
metabolites with many medicinal properties, including the essential anti-cancer therapeutics …

Drug discovery from medicinal plants

MJ Balunas, AD Kinghorn - Life sciences, 2005 - Elsevier
Current research in drug discovery from medicinal plants involves a multifaceted approach
combining botanical, phytochemical, biological, and molecular techniques. Medicinal plant …

Monoterpenes and their derivatives—Recent development in biological and medical applications

M Zielińska-Błajet, J Feder-Kubis - International Journal of Molecular …, 2020 - mdpi.com
Monoterpenes, comprising hydrocarbons, are the largest class of plant secondary
metabolites and are commonly found in essential oils. Monoterpenes and their derivatives …

Transcriptional regulatory network of high-value active ingredients in medicinal plants

H Zheng, X Fu, J Shao, Y Tang, M Yu, L Li… - Trends in Plant …, 2023 - cell.com
High-value active ingredients in medicinal plants have attracted research attention because
of their benefits for human health, such as the antimalarial artemisinin, anticardiovascular …

Traditional medicines in Africa: an appraisal of ten potent African medicinal plants

MF Mahomoodally - Evidence‐Based Complementary and …, 2013 - Wiley Online Library
The use of medicinal plants as a fundamental component of the African traditional
healthcare system is perhaps the oldest and the most assorted of all therapeutic systems. In …

Chemistry and biology of monoterpene indole alkaloid biosynthesis

SE O'Connor, JJ Maresh - Natural product reports, 2006 - pubs.rsc.org
Chemistry and biology of monoterpene indole alkaloid biosynthesis - Natural Product Reports
(RSC Publishing) DOI:10.1039/B512615K Royal Society of Chemistry View PDF …

De novo production of the plant-derived alkaloid strictosidine in yeast

S Brown, M Clastre, V Courdavault… - Proceedings of the …, 2015 - National Acad Sciences
The monoterpene indole alkaloids are a large group of plant-derived specialized
metabolites, many of which have valuable pharmaceutical or biological activity. There are∼ …

Catharanthus roseus (L.) G. Don: A review of its ethnobotany, phytochemistry, ethnopharmacology and toxicities

S Kumar, B Singh, R Singh - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Catharanthus roseus (L.) G. Don is a well known
medicinal plant belonging to family Apocynaceae that have been traditionally used as …