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The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …
While the raw data for the vast majority are fully publicly available testifying to the …
[HTML][HTML] Population genomics of post-glacial western Eurasia
Western Eurasia witnessed several large-scale human migrations during the Holocene,,,–.
Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced …
Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced …
New insights into human immunity from ancient genomics
Population genetic studies have clearly indicated that immunity and host defense are among
the functions most frequently subject to natural selection, and increased our understanding …
the functions most frequently subject to natural selection, and increased our understanding …
Tracing the Evolution of Human Immunity Through Ancient DNA
Infections have imposed strong selection pressures throughout human evolution, making the
study of natural selection's effects on immunity genes highly complementary to disease …
study of natural selection's effects on immunity genes highly complementary to disease …
Benchmarking freely available HLA ty** algorithms across varying genes, coverages and ty** resolutions
Identifying the specific human leukocyte antigen (HLA) allele combination of an individual is
crucial in organ donation, risk assessment of autoimmune and infectious diseases and …
crucial in organ donation, risk assessment of autoimmune and infectious diseases and …
Extensive pedigrees reveal the social organization of a Neolithic community
Social anthropology and ethnographic studies have described kinship systems and
networks of contact and exchange in extant populations,,–. However, for prehistoric …
networks of contact and exchange in extant populations,,–. However, for prehistoric …
Population genomics of stone age eurasia
The transitions from foraging to farming and later to pastoralism in Stone Age Eurasia (c. 11-
3 thousand years before present, BP) represent some of the most dramatic lifestyle changes …
3 thousand years before present, BP) represent some of the most dramatic lifestyle changes …
Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation
We present a method for detecting evidence of natural selection in ancient DNA time-series
data that leverages an opportunity not utilized in previous scans: testing for a consistent …
data that leverages an opportunity not utilized in previous scans: testing for a consistent …
[HTML][HTML] Hunter-gatherer admixture facilitated natural selection in Neolithic European farmers
Ancient DNA has revealed multiple episodes of admixture in human prehistory during
geographic expansions associated with cultural innovations. One important example is the …
geographic expansions associated with cultural innovations. One important example is the …
Ancient DNA HLA ty** reveals significant shifts in frequency in Europe since the Neolithic
Computational HLA ty** has surged as a cost-effective strategy to uncover questions
regarding the evolution of the HLA system, enabling immunogenic characterization from …
regarding the evolution of the HLA system, enabling immunogenic characterization from …