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How the PhoP/PhoQ System Controls Virulence and Mg2+ Homeostasis: Lessons in Signal Transduction, Pathogenesis, Physiology, and Evolution
SUMMARY The PhoP/PhoQ two-component system governs virulence, Mg2+ homeostasis,
and resistance to a variety of antimicrobial agents, including acidic pH and cationic …
and resistance to a variety of antimicrobial agents, including acidic pH and cationic …
Salmonella Virulence and Immune Escape
M Wang, IH Qazi, L Wang, G Zhou, H Han - Microorganisms, 2020 - mdpi.com
Salmonella genus represents the most common foodborne pathogens causing morbidity,
mortality, and burden of disease in all regions of the world. The introduction of antimicrobial …
mortality, and burden of disease in all regions of the world. The introduction of antimicrobial …
Assembly and maintenance of lipids at the bacterial outer membrane
E Lundstedt, D Kahne, N Ruiz - Chemical reviews, 2020 - ACS Publications
The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …
environments and provides intrinsic resistance to many antibiotics. This membrane is …
Outer membrane lipid secretion and the innate immune response to gram-negative bacteria
The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that
consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The …
consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The …
Structure of the essential inner membrane lipopolysaccharide–PbgA complex
Lipopolysaccharide (LPS) resides in the outer membrane of Gram-negative bacteria where it
is responsible for barrier function,. LPS can cause death as a result of septic shock, and its …
is responsible for barrier function,. LPS can cause death as a result of septic shock, and its …
Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli
S Shu, W Mi - Nature Communications, 2022 - nature.com
Lipopolysaccharide (LPS) is an essential glycolipid and forms a protective permeability
barrier for most Gram-negative bacteria. In E. coli, LPS levels are under feedback control …
barrier for most Gram-negative bacteria. In E. coli, LPS levels are under feedback control …
YhdP, TamB, and YdbH are redundant but essential for growth and lipid homeostasis of the Gram-negative outer membrane
The bacterial cell envelope is the first line of defense and point of contact with the
environment and other organisms. Envelope biogenesis is therefore crucial for the survival …
environment and other organisms. Envelope biogenesis is therefore crucial for the survival …
Border control: regulating LPS biogenesis
The outer membrane (OM) is a defining feature of Gram-negative bacteria that serves as a
permeability barrier and provides rigidity to the cell. Critical to OM function is establishing …
permeability barrier and provides rigidity to the cell. Critical to OM function is establishing …
YejM modulates activity of the YciM/FtsH protease complex to prevent lethal accumulation of lipopolysaccharide
Lipopolysaccharide (LPS) is an essential glycolipid present in the outer membrane (OM) of
many Gram-negative bacteria. Balanced biosynthesis of LPS is critical for cell viability; too …
many Gram-negative bacteria. Balanced biosynthesis of LPS is critical for cell viability; too …
An essential membrane protein modulates the proteolysis of LpxC to control lipopolysaccharide synthesis in Escherichia coli
EM Fivenson, TG Bernhardt - MBio, 2020 - journals.asm.org
Gram-negative bacteria are surrounded by a complex cell envelope that includes two
membranes. The outer membrane prevents many drugs from entering these cells and is thus …
membranes. The outer membrane prevents many drugs from entering these cells and is thus …