Microbiota succession throughout life from the cradle to the grave

C Martino, AH Dilmore, ZM Burcham… - Nature Reviews …, 2022 - nature.com
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

JP Shaffer, LF Nothias, LR Thompson, JG Sanders… - Nature …, 2022 - nature.com
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …

The oscillating gut microbiome and its effects on host circadian biology

L Litichevskiy, CA Thaiss - Annual review of Nutrition, 2022 - annualreviews.org
The microbial community colonizing the gastrointestinal tract, collectively termed the gut
microbiota, is an important element of the host organism due to its impact on multiple …

Time of sample collection is critical for the replicability of microbiome analyses

C Allaband, A Lingaraju, S Flores Ramos, T Kumar… - Nature …, 2024 - nature.com
As the microbiome field moves from descriptive and associative research to mechanistic and
interventional studies, being able to account for all confounding variables in the …

[HTML][HTML] Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions

L Narunsky-Haziza, GD Sepich-Poore, I Livyatan… - Cell, 2022 - cell.com
Cancer-microbe associations have been explored for centuries, but cancer-associated fungi
have rarely been examined. Here, we comprehensively characterize the cancer mycobiome …

Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes

BJ Russell, SD Brown, N Siguenza, I Mai, AR Saran… - Cell, 2022 - cell.com
Live bacterial therapeutics (LBTs) could reverse diseases by engrafting in the gut and
providing persistent beneficial functions in the host. However, attempts to functionally …

Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome

ACD Machado, SD Brown, A Lingaraju, V Sivaganesh… - Cell reports, 2022 - cell.com
Compositional oscillations of the gut microbiome are essential for normal peripheral
circadian rhythms, both of which are disrupted in diet-induced obesity (DIO). Although time …

[HTML][HTML] Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis

P Sun, C Zhang, Y Huang, J Yang, F Zhou… - Biomedicine & …, 2022 - Elsevier
Background Postmenopausal osteoporosis (PMOP) is a common disease that has
decreased bone strength as its main symptom after menopause. Effective treatment for …

Potential pathophysiological pathways in the complex relationships between OSA and cancer

M Sánchez-de-la-Torre, C Cubillos, OJ Veatch… - Cancers, 2023 - mdpi.com
Simple Summary Previous clinical studies have suggested a relationship between
obstructive sleep apnea and some types of cancer. This relationship is very heterogeneous …

Gut microbiota mediate vascular dysfunction in a murine model of sleep apnoea: effect of probiotics

M Badran, A Khalyfa, AC Ericsson… - European …, 2023 - publications.ersnet.org
Background Obstructive sleep apnoea (OSA) is a chronic prevalent condition characterised
by intermittent hypoxia (IH), and is associated with endothelial dysfunction and coronary …