[PDF][PDF] Damage-associated molecular patterns in inflammatory diseases

JS Roh, DH Sohn - Immune network, 2018 - synapse.koreamed.org
Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that
are released from damaged or dying cells and activate the innate immune system by …

S100 proteins as an important regulator of macrophage inflammation

C **a, Z Braunstein, AC Toomey, J Zhong… - Frontiers in …, 2018 - frontiersin.org
The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins

D Bertheloot, E Latz - Cellular & molecular immunology, 2017 - nature.com
Our immune system is based on the close collaboration of the innate and adaptive immune
systems for the rapid detection of any threats to the host. Recognition of pathogen-derived …

[HTML][HTML] Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases

K Byun, YC Yoo, M Son, J Lee, GB Jeong… - Pharmacology & …, 2017 - Elsevier
Advanced glycation end products (AGEs) and their receptor have been implicated in the
progressions of many intractable diseases, such as diabetes and atherosclerosis, and are …

Functions of S100 proteins

R Donato, BR cannon, G Sorci, F Riuzzi… - Current molecular …, 2013 - ingentaconnect.com
The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Vascular smooth muscle cell in atherosclerosis

DA Chistiakov, AN Orekhov, YV Bobryshev - Acta physiologica, 2015 - Wiley Online Library
Vascular smooth muscle cells (VSMC s) exhibit phenotypic and functional plasticity in order
to respond to vascular injury. In case of the vessel damage, VSMC s are able to switch from …

DAMPening inflammation by modulating TLR signalling

AM Piccinini, KS Midwood - Mediators of inflammation, 2010 - Wiley Online Library
Damage‐associated molecular patterns (DAMPs) include endogenous intracellular
molecules released by activated or necrotic cells and extracellular matrix (ECM) molecules …

Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques

SEP New, C Goettsch, M Aikawa, JF Marchini… - Circulation …, 2013 - Am Heart Assoc
Rationale: We previously showed that early calcification of atherosclerotic plaques
associates with macrophage accumulation. Chronic renal disease and mineral imbalance …

Toll-like receptors in the vascular system: sensing the dangers within

S Goulopoulou, CG McCarthy, RC Webb… - Pharmacological …, 2016 - Elsevier
Toll-like receptors (TLRs) are components of the innate immune system that respond to
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …

The endogenous Toll–like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

JM Ehrchen, C Sunderkötter, D Foell… - Journal of leukocyte …, 2009 - academic.oup.com
Abstract S100A8 and S100A9 are novel members of the group of damage–associated
molecular pattern molecules (DAMP) which are early amplifiers of innate immune responses …