Metastasis is the major cause of mortality in cancer disease and still constitutes one of the
most controversial mechanism, not yet fully understood. What is almost beyond doubt is that …

Liver metastases of colorectal carcinoma occur in about 50–60% of patients. To improve
survival of these patients, there is an urgent need for new treatment strategies. For this …

Introduction In metastasis research, modern microscopic techniques shed a new light on the
mechanisms of metastatic tumor cell arrest in the microcirculation of potential metastasis …

The “genometastasis hypothesis” proposes that cell‐free tumor nucleic acids might be able
to transform host stem cells, and that this might be a pathway for the development of …

The role and clinical significance of circulating tumor cells and of tumor DNA in the plasma
have not yet been clarified. In the present study, we compared rates of detection of tumor …

Background Objective of this study is a feasibility-test comparing hock-and footpad-injection
in rats with inoculated MatLyLu-adenocarcinoma tumor model. This study compares the …

Differential presence of exons (DPE) is a method of interpretation of exome sequencing,
which has been proposed to design a predictive algorithm with clinical value in patients with …

This study aimed to develop a new model of colorectal liver metastases (LM) in the rat. Both
single macroscopic and multiple bilobar microscopic LM were investigated, as this closely …

UNIVERSIDAD DE SALAMANCA FACULTAD DE MEDICINA DEPARTAMENTO DE CIRUGÍA
Cáncer de colon experimental: Caracterización del model Page 1 Tesis Doctoral de F. Roux …