Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances

S Jacob, AB Nair, J Shah, S Gupta, SHS Boddu… - Pharmaceutics, 2022 - mdpi.com
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

Advanced drug delivery systems containing herbal components for wound healing

B Gorain, M Pandey, NH Leng, CW Yan, KW Nie… - International Journal of …, 2022 - Elsevier
Management of chronic wound has an immense impact on social and economic conditions
in the world. Healthcare costs, aging population, physical trauma, and comorbidities of …

Naringenin nano-delivery systems and their therapeutic applications

M Bhia, M Motallebi, B Abadi, A Zarepour… - Pharmaceutics, 2021 - mdpi.com
Naringenin (NRG) is a polyphenolic phytochemical belonging to the class of flavanones and
is widely distributed in citrus fruits and some other fruits such as bergamot, tomatoes, cocoa …

A comprehensive review of natural compounds for wound healing: targeting bioactivity perspective

XT Trinh, NV Long, LT Van Anh, PT Nga… - International Journal of …, 2022 - mdpi.com
Wound healing is a recovering process of damaged tissues by replacing dysfunctional
injured cellular structures. Natural compounds for wound treatment have been widely used …

Chitosan coated clove oil-based nanoemulsion: An attractive option for oral delivery of leflunomide in rheumatoid arthritis

MB Zewail, SA El-Gizawy, GF Asaad… - International Journal of …, 2023 - Elsevier
Rheumatoid arthritis (RA), a distressing inflammatory autoimmune disease, is managed
mainly by Disease-modifying antirheumatic drugs (DMARDs), eg leflunomide (LEF). LEF …

The PI3K-Akt-mTOR and associated signaling pathways as molecular drivers of immune-mediated inflammatory skin diseases: update on therapeutic strategy using …

T Roy, ST Boateng, MB Uddin, S Banang-Mbeumi… - Cells, 2023 - mdpi.com
The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

Preparation and characterization of curcumin nanoemulgel utilizing ultrasonication technique for wound healing: In vitro, ex vivo, and in vivo evaluation

MS Algahtani, MZ Ahmad, IH Nourein, HA Albarqi… - Gels, 2021 - mdpi.com
Hydrogels being a drug delivery system has great significance particularly for topical
application in cutaneous open wound. Its specific physicochemical properties such as non …

[HTML][HTML] Nanoemulsions: Formulation, characterization, biological fate, and potential role against COVID-19 and other viral outbreaks

HH Tayeb, R Felimban, S Almaghrabi… - Colloid and Interface …, 2021 - Elsevier
Viral diseases are emerging as global threats. Severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), that causes coronavirus disease (COVID-19), has severe …

Recent update of toxicity aspects of nanoparticulate systems for drug delivery

S Patnaik, B Gorain, S Padhi, H Choudhury… - European Journal of …, 2021 - Elsevier
Potential research outcomes on nanotechnology-based novel drug delivery systems since
the past few decades attracted the attention of the researchers to overcome the limitations of …

Nose-to-brain delivery of amisulpride-loaded lipid-based poloxamer-gellan gum nanoemulgel: In vitro and in vivo pharmacological studies

D Gadhave, S Tupe, A Tagalpallewar, B Gorain… - International Journal of …, 2021 - Elsevier
Unfavorable side effects of available antipsychotics limit the use of conventional delivery
systems, where limited exposure of the drugs to the systemic circulation could reduce the …