New insights into the formation and the function of lamellipodia and ruffles in mesenchymal cell migration
M Innocenti - Cell Adhesion & Migration, 2018 - Taylor & Francis
Lamellipodia and ruffles are veil-shaped cell protrusions composed of a highly branched
actin filament meshwork assembled by the Arp2/3 complex. These structures not only …
actin filament meshwork assembled by the Arp2/3 complex. These structures not only …
About samples, giving examples: optimized single molecule localization microscopy
A Jimenez, K Friedl, C Leterrier - Methods, 2020 - Elsevier
Super-resolution microscopy has profoundly transformed how we study the architecture of
cells, revealing unknown structures and refining our view of cellular assemblies. Among the …
cells, revealing unknown structures and refining our view of cellular assemblies. Among the …
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein
The dynamin GTPase is known to bundle actin filaments, but the underlying molecular
mechanism and physiological relevance remain unclear. Our genetic analyses revealed a …
mechanism and physiological relevance remain unclear. Our genetic analyses revealed a …
4polar-STORM polarized super-resolution imaging of actin filament organization in cells
Single-molecule localization microscopy provides insights into the nanometer-scale spatial
organization of proteins in cells, however it does not provide information on their …
organization of proteins in cells, however it does not provide information on their …
Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
D Leyton-Puig, T Isogai, E Argenzio… - Nature …, 2017 - nature.com
Clathrin lattices at the plasma membrane coat both invaginated and flat regions forming
clathrin-coated pits and clathrin plaques, respectively. The function and regulation of clathrin …
clathrin-coated pits and clathrin plaques, respectively. The function and regulation of clathrin …
Automating multimodal microscopy with NanoJ-Fluidics
Combining and multiplexing microscopy approaches is crucial to understand cellular events,
but requires elaborate workflows. Here, we present a robust, open-source approach for …
but requires elaborate workflows. Here, we present a robust, open-source approach for …
mTORC1 and mTORC2 converge on the Arp2/3 complex to promote KrasG12D-induced acinar-to-ductal metaplasia and early pancreatic carcinogenesis
Y Zhao, B Schoeps, D Yao, Z Zhang, K Schuck… - Gastroenterology, 2021 - Elsevier
Background & Aims Oncogenic Kras G12D induces neoplastic transformation of pancreatic
acinar cells through acinar-to-ductal metaplasia (ADM), an actin-based morphogenetic …
acinar cells through acinar-to-ductal metaplasia (ADM), an actin-based morphogenetic …
Super-resolved visualization of single DNA-based tension sensors in cell adhesion
Cell-extracellular matrix sensing plays a crucial role in cellular behavior and leads to the
formation of a macromolecular protein complex called the focal adhesion. Despite their …
formation of a macromolecular protein complex called the focal adhesion. Despite their …
Fix your membrane receptor imaging: actin cytoskeleton and CD4 membrane organization disruption by chemical fixation
Single-molecule localization microscopy (SMLM) techniques allow near molecular scale
resolution (~ 20 nm) as well as precise and robust analysis of protein organization at …
resolution (~ 20 nm) as well as precise and robust analysis of protein organization at …
[HTML][HTML] Investigation of red blood cells by atomic force microscopy
Currently, much research is devoted to the study of biological objects using atomic force
microscopy (AFM). This method's resolution is superior to the other non-scanning …
microscopy (AFM). This method's resolution is superior to the other non-scanning …