Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

Cellular decision making is the process whereby cells assume different, functionally
important and heritable fates without an associated genetic or environmental difference …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

Bioelectronics, which converges biology and electronics, has attracted great attention due to
their vital applications in human–machine interfaces. While traditional bioelectronic devices …

The behavior of genetic circuits is often poorly predictable. A gene's expression level is not
only determined by the intended regulators, but also affected by changes in ribosome …

A central goal of synthetic biology is to achieve multi-signal integration and processing in
living cells for diagnostic, therapeutic and biotechnology applications. Digital logic has been …

The heat-shock response is a mechanism of cellular protection against sudden adverse
environmental growth conditions and results in the prompt production of various heat-shock …

Abstract Characterization and standardization of inducible transcriptional regulators has
transformed how scientists approach biology by allowing precise and tunable control of …

Biological systems are robust to perturbation by mutations and environmental fluctuations.
New data are shedding light on the biochemical and network-level mechanisms responsible …

Bacteria cycle between periods when they perform individual behaviors and periods when
they perform group behaviors. These transitions are controlled by a cell–cell communication …