Development and arealization of the cerebral cortex

CR Cadwell, A Bhaduri, MA Mostajo-Radji, MG Keefe… - Neuron, 2019 - cell.com
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

ERK/MAPK signalling in the develo** brain: Perturbations and consequences

JD Iroegbu, OK Ijomone, OM Femi-Akinlosotu… - Neuroscience & …, 2021 - Elsevier
The extracellular regulated kinase/microtubule-associated protein kinase (ERK/MAPK)
signalling pathway transduces signals that cause an alteration in the ongoing metabolic …

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

DP Hibar, LT Westlye, NT Doan, N Jahanshad… - Molecular …, 2018 - nature.com
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well
understood. Structural brain differences have been associated with BD, but results from …

The ASD Living Biology: from cell proliferation to clinical phenotype

E Courchesne, T Pramparo, VH Gazestani… - Molecular …, 2019 - nature.com
Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the
lay public because of its uncertain origins and striking and unexplained clinical …

Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan

C Ecker, SY Bookheimer, DGM Murphy - The Lancet Neurology, 2015 - thelancet.com
Over the past decade, in-vivo MRI studies have provided many invaluable insights into the
neural substrates underlying autism spectrum disorder (ASD), which is now known to be …

[HTML][HTML] MAP/ERK signaling in develo** cognitive and emotional function and its effect on pathological and neurodegenerative processes

H Albert-Gascó, F Ros-Bernal… - International journal of …, 2020 - mdpi.com
The signaling pathway of the microtubule-associated protein kinase or extracellular
regulated kinase (MAPK/ERK) is a common mechanism of extracellular information …

Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids

M Notaras, A Lodhi, F Dündar, P Collier… - Molecular …, 2022 - nature.com
Due to an inability to ethically access develo** human brain tissue as well as identify
prospective cases, early-arising neurodevelopmental and cell-specific signatures of …

Association of structural magnetic resonance imaging measures with psychosis onset in individuals at clinical high risk for develo** psychosis: an ENIGMA working …

M Jalbrzikowski, RA Hayes, SJ Wood… - JAMA …, 2021 - jamanetwork.com
Importance The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled
neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological …

Proliferation control in neural stem and progenitor cells

CCF Homem, M Repic, JA Knoblich - Nature Reviews Neuroscience, 2015 - nature.com
Neural circuit function can be drastically affected by variations in the number of cells that are
produced during development or by a reduction in adult cell number owing to disease. For …

Growth and folding of the mammalian cerebral cortex: from molecules to malformations

T Sun, RF Hevner - Nature Reviews Neuroscience, 2014 - nature.com
The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …