Insight into cellular uptake and intracellular trafficking of nanoparticles
Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …
defining new technological platforms. This is perhaps even more evident in the field of …
[HTML][HTML] Endocytosis: the nanoparticle and submicron nanocompounds gateway into the cell
Nanoparticles (NPs) and submicron particles are increasingly used as carriers for delivering
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …
How softness matters in soft nanogels and nanogel assemblies
Softness plays a key role in determining the macroscopic properties of colloidal systems,
from synthetic nanogels to biological macromolecules, from viruses to star polymers …
from synthetic nanogels to biological macromolecules, from viruses to star polymers …
Endocytosis at the nanoscale
I Canton, G Battaglia - Chemical Society Reviews, 2012 - pubs.rsc.org
Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …
macromolecules via deformation of the membrane and generation of membrane-bound …
Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation
Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest
molecules with a capability to respond to external stimuli that can be used for a multitude of …
molecules with a capability to respond to external stimuli that can be used for a multitude of …
Role of nanoparticle mechanical properties in cancer drug delivery
The physicochemical properties of nanoparticles play critical roles in regulating nano-bio
interactions. Whereas the effects of the size, shape, and surface charge of nanoparticles on …
interactions. Whereas the effects of the size, shape, and surface charge of nanoparticles on …
Nanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein AI in corona formation
M Li, X **, T Liu, F Fan, F Gao, S Chai… - Nature communications, 2022 - nature.com
Nanoparticle elasticity is crucial in nanoparticles' physiological fate, but how this occurs is
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
The journey of a drug-carrier in the body: an anatomo-physiological perspective
Recent advances in chemistry and material sciences have witnessed the emergence of an
increasing number of novel and complex nanosized carriers for the delivery of drugs and …
increasing number of novel and complex nanosized carriers for the delivery of drugs and …
Nanoparticle elasticity directs tumor uptake
To date, the role of elasticity in drug delivery remains elusive due to the inability to measure
microscale mechanics and alter rheology without affecting chemistry. Herein, we describe …
microscale mechanics and alter rheology without affecting chemistry. Herein, we describe …
Chemical basis of interactions between engineered nanoparticles and biological systems
As defined by the European Commission, a nanomaterial is a natural, an incidental, or a
manufactured material containing particles in an unbound state or as an aggregate or …
manufactured material containing particles in an unbound state or as an aggregate or …