Arylamine N‐acetyltransferases (NAT s) are polymorphic drug‐metabolizing enzymes,
acetylating arylamine carcinogens and drugs including hydralazine and sulphonamides …

Arylamine N‐acetyltransferase (NAT) plays an important role in metabolism and
detoxification of many compounds including drugs and environmental carcinogens through …

Cyclic AMP synthesized by Mycobacterium tuberculosis has been shown to play a role in
pathogenesis. However, the high levels of intracellular cAMP found in both pathogenic and …

A synopsis of eukaryotic Nα-terminal acetyltransferases: nomenclature, subunits and substrates
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Rationale: Standardized dosing of antitubercular drugs leads to variable plasma drug levels,
which are associated with adverse drug reactions, delayed treatment response, and relapse …

Microbes encounter a broad spectrum of antimicrobial compounds in their environments and
often possess metabolic strategies to detoxify such xenobiotics. We have previously shown …

Arylamine N-acetyltransferases (NATs) are defined as xenobiotic metabolizing enzymes,
adding an acetyl group from acetyl coenzyme A (CoA) to arylamines and arylhydrazines …

Influenza represents a major and ongoing public health hazard. Current collaborative efforts
are aimed toward creating a universal flu vaccine with the goals of both improving …

Human arylamine N‐acetyltransferase 1 (NAT1) is a phase II xenobiotic metabolizing
enzyme found in almost all tissues. NAT1 can also hydrolyze acetyl‐coenzyme A (acetyl …

Elevated expression of N‐acetyltransferase 1 (NAT1) is associated with invasive and lobular
breast carcinomas as well as with bone metastasis following an epithelial‐to‐mesenchymal …