Cross-species RNA-seq for deciphering host–microbe interactions

AJ Westermann, J Vogel - Nature Reviews Genetics, 2021 - nature.com
The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …

The osteoporosis/microbiota linkage: the role of miRNA

M De Martinis, L Ginaldi, A Allegra, MM Sirufo… - International Journal of …, 2020 - mdpi.com
Hundreds of trillions of bacteria are present in the human body in a mutually beneficial
symbiotic relationship with the host. A stable dynamic equilibrium exists in healthy …

The regulatory role of N6‐methyladenosine modification in the interaction between host and microbes

R Zhuo, M Xu, X Wang, B Zhou, X Wu… - Wiley …, 2022 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) is the most prevalent posttranscriptional modification in
eukaryotic mRNAs. Dynamic and reversible m6A modification regulates gene expression to …

MicroRNAs in the interaction between host–bacterial pathogens: A new perspective

Z Riahi Rad, Z Riahi Rad, H Goudarzi… - Journal of cellular …, 2021 - Wiley Online Library
Gene expression regulation plays a critical role in host–pathogen interactions, and RNAs
function is essential in this process. miRNAs are small noncoding, endogenous RNA …

Understanding microRNAs in the context of infection to find new treatments against human bacterial pathogens

Á Mourenza, B Lorente-Torres, E Durante… - Antibiotics, 2022 - mdpi.com
The development of RNA-based anti-infectives has gained interest with the successful
application of mRNA-based vaccines. Small RNAs are molecules of RNA of< 200 …

[HTML][HTML] Oral Spirochete Treponema denticola Intraoral Infection Reveals Unique miR-133a, miR-486, miR-126-3p, miR-126-5p miRNA Expression Kinetics during …

C Aravindraja, S Jeepipalli, KM Vekariya… - International Journal of …, 2023 - mdpi.com
miRNAs are major regulators of eukaryotic gene expression and host immunity, and play an
important role in the inflammation-mediated pathways in periodontal disease (PD) …

Salmonella enterica serovar Typhimurium SPI-1 and SPI-2 shape the global transcriptional landscape in a human intestinal organoid model system

ALE Lawrence, BH Abuaita, RP Berger, DR Hill… - MBio, 2021 - journals.asm.org
The intestinal epithelium is a primary interface for engagement of the host response by
foodborne pathogens, like Salmonella enterica Typhimurium. While the interaction of S …

Leishmania highjack host lipid body for its proliferation in macrophages by overexpressing host Rab18 and TRAPPC9 by downregulating miR-1914-3p expression

C Sood, JK Verma, R Basak, A Kapoor, S Gupta… - PLoS …, 2024 - journals.plos.org
Lipids stored in lipid-bodies (LBs) in host cells are potential sources of fatty acids for
pathogens. However, the mechanism of recruitment of LBs from the host cells by pathogens …

[HTML][HTML] MiR-20a-5p Targeting the TGFBR2 Gene Regulates Inflammatory Response of Chicken Macrophages Infected with Avian Pathogenic E. coli

X Cao, J Ge, Y Ma, H Li, W Han, SJ Lamont, H Sun - Animals, 2024 - mdpi.com
Simple Summary Avian pathogenic E. coli (APEC) causes localized and systemic infections
that are collectively known as avian colibacillosis. In the poultry industry, APEC infections …