Reactive oxygen species‐induced lipid peroxidation in apoptosis, autophagy, and ferroptosis

LJ Su, JH Zhang, H Gomez, R Murugan… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species‐(ROS‐) induced lipid peroxidation plays a critical role in cell death
including apoptosis, autophagy, and ferroptosis. This fundamental and conserved …

Targeting cell death: pyroptosis, ferroptosis, apoptosis and necroptosis in osteoarthritis

J Yang, S Hu, Y Bian, J Yao, D Wang, X Liu… - Frontiers in cell and …, 2022 - frontiersin.org
New research has shown that the development of osteoarthritis (OA) is regulated by different
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …

The concept of intrinsic versus extrinsic apoptosis

L Lossi - Biochemical Journal, 2022 - portlandpress.com
Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …

Natural killer cells: development, maturation, and clinical utilization

AM Abel, C Yang, MS Thakar… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

The role of natural killer cells in autoimmune diseases

UC Kucuksezer, E Aktas Cetin, F Esen… - Frontiers in …, 2021 - frontiersin.org
Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …

The PANoptosome: a deadly protein complex driving pyroptosis, apoptosis, and necroptosis (PANoptosis)

P Samir, RKS Malireddi, TD Kanneganti - Frontiers in cellular and …, 2020 - frontiersin.org
Programmed cell death is regulated by evolutionarily conserved pathways that play critical
roles in development and the immune response. A newly recognized pathway for …

The mitochondrial pathway of apoptosis Part I: MOMP and beyond

DR Green - Cold Spring Harbor Perspectives in Biology, 2022 - cshperspectives.cshlp.org
The major mode of apoptosis in vertebrates is the mitochondrial pathway. This pathway of
cell death is engaged by a vast array of cell stresses, including deprivation of growth factors …

Initiation and perpetuation of NLRP 3 inflammasome activation and assembly

EI Elliott, FS Sutterwala - Immunological reviews, 2015 - Wiley Online Library
The NLRP 3 (NOD‐like receptor family, pyrin domain containing 3) inflammasome is a
multiprotein complex that orchestrates innate immune responses to infection and cell stress …

Extracellular vesicles and exosomes: insights from exercise science

JP Nederveen, G Warnier, A Di Carlo… - Frontiers in …, 2021 - frontiersin.org
The benefits of exercise on health and longevity are well-established, and evidence
suggests that these effects are partially driven by a spectrum of bioactive molecules …

Apoptosis and clearance of apoptotic cells

S Nagata - Annual review of immunology, 2018 - annualreviews.org
The human body generates 10–100 billion cells every day, and the same number of cells
die to maintain homeostasis in our body. Cells infected by bacteria or viruses also die. The …