Amorphization technology has been the subject of continuous attention in the
pharmaceutical industry, as a means to enhance the solubility of poorly water-soluble drugs …

There has been a tremendous revolution in the field of nanotechnology, resulting in the
advent of novel drug delivery systems known as nanomedicines for diagnosis and therapy …

The complexation of polyelectrolytes with other oppositely charged structures gives rise to a
great variety of functional materials with potential applications in a wide spectrum of …

Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical
Classification System (BCS) because of its poor aqueous solubility. In this study, we …

Poor aqueous solubility is currently a prevalent issue in the development of small molecule
pharmaceuticals. Several methods are possible for improving the solubility, dissolution rate …

The objective of this study was to formulate nano-amorphous spray-dried powders of
itraconazole to enhance its oral bioavailability. A combination approach of solvent …

The development of novel antibiotic systems is needed to address the methicillin-resistant
Staphylococcus aureus (MRSA) infections. The aim of the study was to explore the novel …

A promising approach to increase the aqueous solubility, hence the bioavailability, of poorly
water-soluble drugs is to convert them into their amorphous state through impregnation into …

Amorphous nanodrugs prepared by electrostatic complexation of drug molecules with
oppositely charged polysaccharides represent a promising bioavailability enhancement …

Objective: In the present work nanocrystal-based formulation of risperidone (RIS) was
proposed to overcome solubility issue of RIS, while lyophilization technique was used …