This review discusses the current state of the viral metabolism field and gaps in knowledge
that will be important for future studies to investigate. We discuss metabolic rewiring caused …

Members of the Flaviviridae virus family comprise a large group of enveloped viruses with a
single-strand RNA genome of positive polarity. Several genera belong to this family …

Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

To ensure optimal environments for their replication and spread, viruses have evolved to
alter many host cell pathways. In the last decade, metabolomic studies have shown that …

Infections with flaviviruses, such as dengue, West Nile virus and the recently re-emerging
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …

Viral replication is a process that involves an extremely high turnover of cellular molecules.
Since viruses depend on the host cell to obtain the macromolecules needed for their proper …

Viruses rely on host cellular metabolism to provide the energy and biosynthetic building
blocks required for their replication. Dengue virus (DENV), a member of the Flaviviridae …

Ubiquitylation is one of the most versatile protein post-translational modifications and is
frequently altered during virus infections. Here we employed a functional proteomics screen …

Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral
pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever …

Dengue virus (DENV) is the most prevalent medically important mosquito-borne virus in the
world. Upon DENV infection of a host cell, DENV nonstructural protein 1 (NS1) can be found …