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The life cycle of non-polio enteroviruses and how to target it
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
Current progress in antiviral strategies
Z Lou, Y Sun, Z Rao - Trends in pharmacological sciences, 2014 - cell.com
The prevalence of chronic viral infectious diseases, such as human immunodeficiency virus
(HIV), hepatitis C virus (HCV), and influenza virus; the emergence and re-emergence of new …
(HIV), hepatitis C virus (HCV), and influenza virus; the emergence and re-emergence of new …
Hepatitis A virus and the origins of picornaviruses
Hepatitis A virus (HAV) remains enigmatic, despite 1.4 million cases worldwide annually. It
differs radically from other picornaviruses, existing in an enveloped form and being …
differs radically from other picornaviruses, existing in an enveloped form and being …
Sialic acid-dependent cell entry of human enterovirus D68
Abstract Human enterovirus D68 (EV-D68) is a causative agent of childhood respiratory
diseases and has now emerged as a global public health threat. Nevertheless, knowledge …
diseases and has now emerged as a global public health threat. Nevertheless, knowledge …
Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2
Abstract Enterovirus 71 (EV71) is a common cause of hand, foot and mouth disease—a
disease endemic especially in the Asia-Pacific region. Scavenger receptor class B member …
disease endemic especially in the Asia-Pacific region. Scavenger receptor class B member …
[HTML][HTML] Shake, rattle, and roll: Impact of the dynamics of flavivirus particles on their interactions with the host
Remarkable progress in structural biology has equipped virologists with insight into
structures of viral proteins and virions at increasingly high resolution. Structural information …
structures of viral proteins and virions at increasingly high resolution. Structural information …
Foot-and-mouth disease virus antigenic landscape and reduced immunogenicity elucidated in atomic detail
Unlike most other picornaviruses, foot-and-mouth disease (FMD) intact virions (146S)
dissociate easily into small pentameric subunits (12S). This causes a dramatically …
dissociate easily into small pentameric subunits (12S). This causes a dramatically …
Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71
Unlike the well-established picture for the entry of enveloped viruses, the mechanism of
cellular entry of non-enveloped eukaryotic viruses remains largely mysterious …
cellular entry of non-enveloped eukaryotic viruses remains largely mysterious …
Enteroviral proteases: structure, host interactions and pathogenicity
Enteroviruses are common human pathogens, and infections are particularly frequent in
children. Severe infections can lead to a variety of diseases, including poliomyelitis, aseptic …
children. Severe infections can lead to a variety of diseases, including poliomyelitis, aseptic …
Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design
Virus capsids are primed for disassembly, yet capsid integrity is key to generating a
protective immune response. Foot-and-mouth disease virus (FMDV) capsids comprise …
protective immune response. Foot-and-mouth disease virus (FMDV) capsids comprise …