Whole‐body endothermy: ancient, homologous and widespread among the ancestors of mammals, birds and crocodylians

G Grigg, J Nowack, JEPW Bicudo, NC Bal… - Biological …, 2022 - Wiley Online Library
The whole‐body (tachymetabolic) endothermy seen in modern birds and mammals is long
held to have evolved independently in each group, a reasonable assumption when it was …

Human brown adipose tissue and metabolic health: potential for therapeutic avenues

R Singh, A Barrios, G Dirakvand, S Pervin - Cells, 2021 - mdpi.com
Obesity-associated metabolic abnormalities comprise a cluster of conditions including
dyslipidemia, insulin resistance, diabetes and cardiovascular diseases that has affected …

AMP-activated protein kinase (AMPK) regulates energy metabolism through modulating thermogenesis in adipose tissue

L Wu, L Zhang, B Li, H Jiang, Y Duan, Z **e… - Frontiers in …, 2018 - frontiersin.org
Obesity occurs when excess energy accumulates in white adipose tissue (WAT), whereas
brown adipose tissue (BAT), which is specialized in dissipating energy through …

Adipose tissue adipokines and lipokines: Functions and regulatory mechanism in skeletal muscle development and homeostasis

X Gu, L Wang, S Liu, T Shan - Metabolism, 2023 - Elsevier
Skeletal muscle plays important roles in normal biological activities and whole-body energy
homeostasis in humans. The growth and development of skeletal muscle also directly …

Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis

NC Bal, M Periasamy - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
Thermogenesis in endotherms relies on both shivering and non-shivering thermogenesis
(NST). The role of brown adipose tissue (BAT) in NST is well recognized, but the role of …

Adipose tissue depot differences in adipokines and effects on skeletal and cardiac muscle

A Rodríguez, S Becerril, AW Hernández-Pardos… - Current opinion in …, 2020 - Elsevier
White (WAT) and brown (BAT) adipose tissue communicate with skeletal muscle and heart
through the secretion of adipokines (adiponectin, leptin, omentin, osteopontin or …

Avian adjustments to cold and non‐shivering thermogenesis: whats, wheres and hows

P Pani, NC Bal - Biological Reviews, 2022 - Wiley Online Library
Avian cold adaptation is hallmarked by innovative strategies of both heat conservation and
thermogenesis. While minimizing heat loss can reduce the thermogenic demands of body …

Interleukin-6 released from differentiating human beige adipocytes improves browning

E Kristóf, Á Klusóczki, R Veress, A Shaw… - Experimental cell …, 2019 - Elsevier
Brown and beige adipocytes contribute significantly to the regulation of whole body energy
expenditure and systemic metabolic homeostasis not exclusively by thermogenesis through …

Effects of multi-organ crosstalk on the physiology and pathology of adipose tissue

S Wang, Y Liu, J Chen, Y He, W Ma, X Liu… - Frontiers in …, 2023 - frontiersin.org
In previous studies, adipocytes were found to play an important role in regulating whole-
body nutrition and energy balance, and are also important in energy metabolism, hormone …

[HTML][HTML] The potential roles of myokines in adipose tissue metabolism with exercise and cold exposure

S Jiang, JH Bae, Y Wang, W Song - International journal of molecular …, 2022 - mdpi.com
Exercise and cold exposure are two stimuli that have been suggested as solely effective to
modulate adipose tissue metabolism and improve metabolic health in obese populations …