The expression of CD4 and CD8 co-receptors defines two distinct T cell populations with
specialized functions. While CD4+ T cells support and modulate immune responses through …

Diabetes, a chronic metabolic disorder disrupting blood sugar regulation, has emerged as a
prominent silent pandemic. Uncontrolled diabetes predisposes an individual to develop fatal …

Hantaan virus (HTNV) infection causes an epidemic of hemorrhagic fever with renal
syndrome (HFRS) mainly in Asia. It is well known that T cells mediated anti-viral immune …

Purposes We aimed to investigate the levels of CD4+ CD8+ double positive (DP) T cells in
patients with various severities of hemorrhagic fever with renal syndrome (HFRS), and the …

HIV-infected patients are at higher risk of develo** oral mucosal infection and Epstein–
Barr virus (EBV)-associated B cell malignancies. However, the potential role of oral immunity …

There are a limited number of effective vaccines against dengue virus (DENV) and
significant efforts are being made to develop potent anti-virals. Previously, we described that …

Abstract CD4+ and CD8+ T cells play critical roles in both innate and adaptive immune
responses, managing and modulating cellular immunity during immune diseases and …

Communication between immune cells through direct contact is a critical feature of immune
responses. Here, we developed a novel high-throughput method to study the transcriptome …

Objective The establishment of reference values for a subset of leukocytes is common in
clinical practice, and ethnic variations are strongly associated with disease development. In …

Dengue (DENV) virus and Zika virus (ZIKV) are two flaviviruses of major public health
concern. One drawback designing effective vaccines is our limited understanding of the …