Assessment of candidate genes and genetic heterogeneity in human non syndromic orofacial clefts specifically non syndromic cleft lip with or without palate

K Saleem, T Zaib, W Sun, S Fu - Heliyon, 2019 - cell.com
Non syndromic orofacial clefts specifically non-syndromic cleft lip/palate are one of the most
common craniofacial malformation among birth defects in human having multifactorial …

Bone regeneration capacities of alveolar bone mesenchymal stem cells sheet in rabbit calvarial bone defect

Y Liu, H Wang, H Dou, B Tian, L Li… - Journal of tissue …, 2020 - journals.sagepub.com
Mesenchymal stem cells sheets have been verified as a promising non-scaffold strategy for
bone regeneration. Alveolar bone marrow mesenchymal stem cells, derived from neural …

Median cleft of the upper lip: a new classification to guide treatment decisions

M de Boutray, JL Beziat, J Yachouh, M Bigorre… - Journal of Cranio …, 2016 - Elsevier
Median cleft of the upper lip (MCL) is a specific and rare entity on the spectrum of facial
clefts. MCL have different clinical expressions and can be either isolated or part of multiple …

[HTML][HTML] The impact of developmental genes in non-syndromic cleft lip and/or palate

NŞ Uysal, Fİ Şahin, YK Terzi - Journal of the Turkish German …, 2023 - ncbi.nlm.nih.gov
Non-syndromic cleft lip and/or palate (NSCL/P) is a congenital malformation with a
prevalence of 1: 700 births. It has a multifactorial etiology. Human craniofacial development …

The intersection of the genetic architectures of orofacial clefts and normal facial variation

K Indencleef, H Hoskens, MK Lee, JD White… - Frontiers in …, 2021 - frontiersin.org
Unaffected relatives of individuals with non-syndromic cleft lip with or without cleft palate
(NSCL/P) show distinctive facial features. The presence of this facial endophenotype is …

Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans

LA Lansdon, BW Darbro, AL Petrin, AM Hulstrand… - Genetics, 2018 - academic.oup.com
Orofacial clefts are one of the most common birth defects, affecting 1–2 per 1000 births, and
have a complex etiology. High-resolution array-based comparative genomic hybridization …

Discovery of candidate genes for nonsyndromic cleft lip palate through genome-wide linkage analysis of large extended families in the Malay population

NS Mohamad Shah, I Salahshourifar, S Sulong… - BMC genetics, 2016 - Springer
Background Nonsyndromic orofacial clefts are one of the most common birth defects
worldwide. It occurs as a result of genetic or environmental factors. This study investigates …

Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2

JM Cesario, A Landin Malt, LJ Deacon… - Human molecular …, 2015 - academic.oup.com
Cleft palate is a common birth defect in humans. Therefore, understanding the molecular
genetics of palate development is important from both scientific and medical perspectives …

Partial deletion of chromosome 1p31. 1 including only the neuronal growth regulator 1 gene in two siblings

A Genovese, DM Cox, MG Butler - Journal of pediatric genetics, 2015 - thieme-connect.com
We present two siblings with a partial deletion of chromosome 1p31. 1 involving only the
neuronal growth regulator 1 (NEGR1) gene. The siblings had a history of neuropsychiatric …

Two novel genes TOX3 and COL21A1 in large extended Malay families with nonsyndromic cleft lip and/or palate

NS Mohamad Shah, S Sulong… - … Genetics & Genomic …, 2019 - Wiley Online Library
Background Nonsyndromic cleft lip and/or palate is one of the most common human birth
defects worldwide that affects the lip and/or palate. The incidence of clefts varies among …